卡马替尼 (CAS No.1029712-80-8)
- 物化性质
- 白色至类白色固体粉末,溶于二甲基亚砜(DMSO),微溶于乙醇,几乎不溶于水。分子量412.42。需在-20°C密封避光干燥保存。
- 纯度
- ≥99% (HPLC)
- 储存条件
- -20°C,密封避光保存
- 溶解性
- 溶于DMSO,微溶于乙醇,几乎不溶于水
English description(英文原文,共 1022 字符)
Product Name:Capmatinib
English Name:Capmatinib
CAS No.:1029712-80-8
Aliases:INC280, INCB28060
Molecular Formula:C23H17FN6O
Physical Properties:White to off-white solid powder; soluble in dimethyl sulfoxide (DMSO), slightly soluble in ethanol, practically insoluble in water. Molecular weight: 412.42. Store at -20°C in a sealed, dry, light-protected condition.
Uses:Capmatinib is a selective MET receptor tyrosine kinase inhibitor that exerts antitumor activity by inhibiting MET phosphorylation and downstream signaling pathways. It is mainly used in research on non-small cell lung cancer with MET exon 14 skipping mutations, as well as mechanistic studies and drug development for tumors associated with MET pathway activation.
Technical Specifications:
Purity: ≥99% (HPLC)
Molecular formula: C23H17FN6O, molecular weight: 412.42
Packaging: available in mg and g scales
Storage: -20°C, sealed and protected from light
Solubility: soluble in DMSO, slightly soluble in ethanol, practically insoluble in water
English Name:Capmatinib
CAS No.:1029712-80-8
Aliases:INC280, INCB28060
Molecular Formula:C23H17FN6O
Physical Properties:White to off-white solid powder; soluble in dimethyl sulfoxide (DMSO), slightly soluble in ethanol, practically insoluble in water. Molecular weight: 412.42. Store at -20°C in a sealed, dry, light-protected condition.
Uses:Capmatinib is a selective MET receptor tyrosine kinase inhibitor that exerts antitumor activity by inhibiting MET phosphorylation and downstream signaling pathways. It is mainly used in research on non-small cell lung cancer with MET exon 14 skipping mutations, as well as mechanistic studies and drug development for tumors associated with MET pathway activation.
Technical Specifications:
Purity: ≥99% (HPLC)
Molecular formula: C23H17FN6O, molecular weight: 412.42
Packaging: available in mg and g scales
Storage: -20°C, sealed and protected from light
Solubility: soluble in DMSO, slightly soluble in ethanol, practically insoluble in water
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- 卡马替尼的分子式为 C23H17FN6O。
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- 卡马替尼又称 INC280、INCB28060。
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