1,3-二-O-(叔-丁基二甲基硅烷基)卡泊三醇 (CAS No.112875-61-3)
- 中文别名
- 1,3-双(叔丁基二甲基硅烷基)卡泊三醇；卡泊三醇双TBS醚；1,3-二-O-TBS-卡泊三醇
- 英文名称
- 1,3-Di-O-(tert-butyldimethylsilyl)calcipotriol
- 分子式
- C39H68O3Si2
- 分子量
- 640.05（按C39H68O3Si2计算）。
- InChIKey
- DIMYHZDULFSWLS-OABMYDGKSA-N
- 所属类别
- 中间体
- 物化性质
- 白色至类白色结晶粉末；溶于二氯甲烷、乙酸乙酯、甲醇和氯仿等有机溶剂，几乎不溶于水；对酸敏感，酸性条件下可脱除叔丁基二甲基硅烷基保护基；应密封、避光、低温干燥储存。
- 外观
- 白色至类白色粉末。
- 纯度
- HPLC测定纯度不低于95%。
- 储存条件
- 密封，2-8°C避光保存。
- 溶解性
- 易溶于二氯甲烷、乙酸乙酯、甲醇和氯仿等有机溶剂。
English description（英文原文，共 1308 字符）
Product Name:1,3-Di-O-(tert-butyldimethylsilyl)calcipotriol
English Name:1,3-Di-O-(tert-butyldimethylsilyl)calcipotriol
CAS No.:112875-61-3
Aliases:1,3-Bis-O-(tert-butyldimethylsilyl)calcipotriol, Calcipotriol bis-TBS ether, 1,3-Di-TBS-calcipotriol
Molecular Formula:C39H68O3Si2
Physical Properties:White to off-white crystalline powder; soluble in organic solvents such as dichloromethane, ethyl acetate, methanol, and chloroform, nearly insoluble in water; sensitive to acid, the tert-butyldimethylsilyl protecting groups can be removed under acidic conditions; should be stored sealed, protected from light, and kept at low temperature in a dry environment.
Uses:Used as a key hydroxyl-protecting intermediate in the synthesis of calcipotriol and other vitamin D derivatives. The TBS group selectively protects the 1,3-hydroxy groups of calcipotriol for multi-step synthesis, with the target drug obtained by final deprotection. Also applicable to the preparation of other vitamin D analogs.
Technical Specifications:
Appearance: white to off-white powder.
Purity: HPLC purity not less than 95%.
Molecular weight: 640.05 (calculated as C39H68O3Si2).
Storage: sealed, stored at 2-8°C protected from light.
Solubility: readily soluble in dichloromethane, ethyl acetate, methanol, and chloroform.
English Name:1,3-Di-O-(tert-butyldimethylsilyl)calcipotriol
CAS No.:112875-61-3
Aliases:1,3-Bis-O-(tert-butyldimethylsilyl)calcipotriol, Calcipotriol bis-TBS ether, 1,3-Di-TBS-calcipotriol
Molecular Formula:C39H68O3Si2
Physical Properties:White to off-white crystalline powder; soluble in organic solvents such as dichloromethane, ethyl acetate, methanol, and chloroform, nearly insoluble in water; sensitive to acid, the tert-butyldimethylsilyl protecting groups can be removed under acidic conditions; should be stored sealed, protected from light, and kept at low temperature in a dry environment.
Uses:Used as a key hydroxyl-protecting intermediate in the synthesis of calcipotriol and other vitamin D derivatives. The TBS group selectively protects the 1,3-hydroxy groups of calcipotriol for multi-step synthesis, with the target drug obtained by final deprotection. Also applicable to the preparation of other vitamin D analogs.
Technical Specifications:
Appearance: white to off-white powder.
Purity: HPLC purity not less than 95%.
Molecular weight: 640.05 (calculated as C39H68O3Si2).
Storage: sealed, stored at 2-8°C protected from light.
Solubility: readily soluble in dichloromethane, ethyl acetate, methanol, and chloroform.
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常见问题
- 1,3-二-O-(叔-丁基二甲基硅烷基)卡泊三醇的 CAS 号是多少？
- 1,3-二-O-(叔-丁基二甲基硅烷基)卡泊三醇的 CAS 号是 112875-61-3。
- 1,3-二-O-(叔-丁基二甲基硅烷基)卡泊三醇的分子式和分子量是什么？
- 1,3-二-O-(叔-丁基二甲基硅烷基)卡泊三醇的分子式为 C39H68O3Si2，分子量约 640.05（按C39H68O3Si2计算）。。
- 1,3-二-O-(叔-丁基二甲基硅烷基)卡泊三醇的英文名称是什么？
- 1,3-二-O-(叔-丁基二甲基硅烷基)卡泊三醇的英文名称为 1,3-Di-O-(tert-butyldimethylsilyl)calcipotriol。
- 1,3-二-O-(叔-丁基二甲基硅烷基)卡泊三醇还有哪些别名？
- 1,3-二-O-(叔-丁基二甲基硅烷基)卡泊三醇又称 1,3-双(叔丁基二甲基硅烷基)卡泊三醇、卡泊三醇双TBS醚、1,3-二-O-TBS-卡泊三醇。
- 1,3-二-O-(叔-丁基二甲基硅烷基)卡泊三醇有哪些供应商和生产厂家？
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