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血管内皮生长因子 (CAS No.127464-60-2)

血管内皮生长因子 127464-60-2
中文别名
人血管内皮生长因子165;重组人VEGF165;血管通透因子
英文名称
Vascular Endothelial Growth Factor 165 (VEGF165)
分子量
还原型SDS-PAGE单体约19 kDa,天然二聚体约38.
所属类别
试剂实验设备
物化性质
重组人血管内皮生长因子165(VEGF165)是由165个氨基酸组成的同源二聚体糖蛋白,还原型单体分子量约19 kDa,二聚体分子量约38.2 kDa。产品为白色至淡黄色冻干粉,可溶于无菌水或PBS(pH 7.4)缓冲液,建议复溶浓度0.1~1.0 mg/mL。冻干粉于-20°C避光保存可稳定存放12个月;复溶后建议4°C保存不超过1周,长期保存需分装后置于-20°C或-80°C,避免反复冻融。
纯度
≥95%(SDS-PAGE电泳考马斯亮蓝染色检测)
外观
白色至淡黄色冻干粉
English description(英文原文,共 1754 字符)
Product Name:Vascular Endothelial Growth Factor 165 (VEGF165)

English Name:Vascular Endothelial Growth Factor 165 (VEGF165)

CAS No.:127464-60-2

Aliases:Human VEGF165, Recombinant Human VEGF165, Vascular Permeability Factor

Physical Properties:Recombinant human vascular endothelial growth factor 165 (VEGF165) is a homodimeric glycoprotein composed of 165 amino acids per monomer, with a molecular weight of approximately 19 kDa for the reduced monomer and 38.2 kDa for the native dimer. The product is supplied as a white to off-white lyophilized powder, soluble in sterile water or PBS buffer (pH 7.4); a reconstitution concentration of 0.1-1.0 mg/mL is recommended. The lyophilized powder is stable for 12 months when stored at -20°C protected from light. After reconstitution, storage at 4°C is recommended for no longer than 1 week; for long-term storage, aliquot and keep at -20°C or -80°C, avoiding repeated freeze-thaw cycles.

Uses:This product is a key cytokine in angiogenesis research, promoting vascular endothelial cell proliferation, migration, and tube formation, and is commonly used as a supplement in endothelial cell culture systems and for mechanistic studies of angiogenesis. It is suitable for in vitro experiments and in vivo animal model administration in angiogenesis-related diseases such as cancer and ischemic disorders, as well as for drug screening and efficacy evaluation studies.

Technical Specifications:

Purity: ≥95% as determined by SDS-PAGE with Coomassie Blue staining

Bioactivity: ED50 ≤10 ng/mL in HUVEC proliferation assay

Endotoxin: ≤0.1 EU/μg by LAL test

Appearance: white to off-white lyophilized powder

Molecular weight: approximately 19 kDa (reduced monomer) and 38.2 kDa (native dimer) by SDS-PAGE
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血管内皮生长因子的 CAS 号是多少?
血管内皮生长因子的 CAS 号是 127464-60-2。
血管内皮生长因子的英文名称是什么?
血管内皮生长因子的英文名称为 Vascular Endothelial Growth Factor 165 (VEGF165)。
血管内皮生长因子还有哪些别名?
血管内皮生长因子又称 人血管内皮生长因子165、重组人VEGF165、血管通透因子。
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