帕布昔利布中间体 (CAS No.1374639-76-5)
- 中文别名
- 6-乙酰基-8-环戊基-5-甲基-2-[[5-(哌嗪-1-基)吡啶-2-基]氨基]-5,8-二氢吡啶并[2,3-d]嘧啶-7(6H)-酮；N-去甲基帕布昔利布；帕布昔利布去甲基代谢物
- 英文名称
- N-Desmethyl Palbociclib
- 分子式
- C23H27N7O2
- 分子量
- 433.51
- 所属类别
- 中间体
- 物化性质
- 白色至类白色结晶性粉末。溶于二氯甲烷、DMSO、DMF等有机溶剂，微溶于甲醇和乙醇，几乎不溶于水。含有碱性哌嗪环，具有一定的吸湿性，在空气中较稳定，建议避光、密封、干燥保存。
- 外观
- 白色至类白色结晶性粉末
- 储存条件
- 密封、避光、干燥处保存，2～8℃最佳
English description（英文原文，共 1169 字符）
Product Name:N-Desmethyl Palbociclib
English Name:N-Desmethyl Palbociclib
CAS No.:1374639-76-5
Aliases:6-Acetyl-8-cyclopentyl-5-methyl-2-{[5-(piperazin-1-yl)pyridin-2-yl]amino}-5,8-dihydropyrido[2,3-d]pyrimidin-7(6H)-one, Palbociclib N-desmethyl metabolite, Desmethyl palbociclib
Molecular Formula:C23H27N7O2
Physical Properties:White to off-white crystalline powder. Soluble in dichloromethane, DMSO and DMF; slightly soluble in methanol and ethanol; practically insoluble in water. Contains a basic piperazine ring, is slightly hygroscopic and relatively stable in air; store protected from light in a tightly closed, dry container.
Uses:This intermediate is a key building block in the synthetic route of palbociclib, a CDK4/6 inhibitor. It also serves as the N-desmethyl metabolite of palbociclib and is commonly used as a metabolite/impurity reference standard in drug analysis, quality control, pharmacokinetic and metabolism studies.
Technical Specifications:
Molecular weight: 433.51
Appearance: white to off-white crystalline powder
Purity (HPLC): ≥98.0%
Loss on drying: ≤0.5%
Storage: keep tightly closed, protected from light, store dry at 2–8 °C
English Name:N-Desmethyl Palbociclib
CAS No.:1374639-76-5
Aliases:6-Acetyl-8-cyclopentyl-5-methyl-2-{[5-(piperazin-1-yl)pyridin-2-yl]amino}-5,8-dihydropyrido[2,3-d]pyrimidin-7(6H)-one, Palbociclib N-desmethyl metabolite, Desmethyl palbociclib
Molecular Formula:C23H27N7O2
Physical Properties:White to off-white crystalline powder. Soluble in dichloromethane, DMSO and DMF; slightly soluble in methanol and ethanol; practically insoluble in water. Contains a basic piperazine ring, is slightly hygroscopic and relatively stable in air; store protected from light in a tightly closed, dry container.
Uses:This intermediate is a key building block in the synthetic route of palbociclib, a CDK4/6 inhibitor. It also serves as the N-desmethyl metabolite of palbociclib and is commonly used as a metabolite/impurity reference standard in drug analysis, quality control, pharmacokinetic and metabolism studies.
Technical Specifications:
Molecular weight: 433.51
Appearance: white to off-white crystalline powder
Purity (HPLC): ≥98.0%
Loss on drying: ≤0.5%
Storage: keep tightly closed, protected from light, store dry at 2–8 °C
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常见问题
- 帕布昔利布中间体的 CAS 号是多少？
- 帕布昔利布中间体的 CAS 号是 1374639-76-5。
- 帕布昔利布中间体的分子式和分子量是什么？
- 帕布昔利布中间体的分子式为 C23H27N7O2，分子量约 433.51。
- 帕布昔利布中间体的英文名称是什么？
- 帕布昔利布中间体的英文名称为 N-Desmethyl Palbociclib。
- 帕布昔利布中间体还有哪些别名？
- 帕布昔利布中间体又称 6-乙酰基-8-环戊基-5-甲基-2-[[5-(哌嗪-1-基)吡啶-2-基]氨基]-5,8-二氢吡啶并[2,3-d]嘧啶-7(6H)-酮、N-去甲基帕布昔利布、帕布昔利布去甲基代谢物。
- 帕布昔利布中间体有哪些供应商和生产厂家？
- 掌上化工当前收录 1 条帕布昔利布中间体供应报价，来自 1 家供应商，可按地区、纯度、级别筛选对比。
- 帕布昔利布中间体的供应商主要分布在哪些地区？
- 帕布昔利布中间体的供应商主要分布在 上海市（1 条） 等地。
- 帕布昔利布中间体有哪些级别可选？
- 平台上帕布昔利布中间体的供应级别包括 工业级。
- 帕布昔利布中间体的报价单位是什么？
- 帕布昔利布中间体的报价单位主要有 千克。
- 哪里可以查到帕布昔利布中间体的价格？
- 掌上化工帕布昔利布中间体产品页汇总了各供应商的最新报价与规格，地址：/chemicals/1374639-76-5/。部分供应商价格为电议，可通过页面上的询价功能直接获取。
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