N-叔丁氧羰基-五聚乙二醇-对甲苯磺酸酯 (CAS No.1404111-69-8)
- 中文别名
- t-Boc-N-amido-PEG5-Tos；Boc-NH-PEG5-Tos；叔丁氧羰基五聚乙二醇对甲苯磺酸酯
- 英文名称
- t-Boc-N-amido-PEG5-Tos
- 分子式
- C22H37NO9S
- 分子量
- 491.60
- 所属类别
- 有机无机原料
- 物化性质
- 本品为亲水性PEG衍生物，五聚乙二醇链赋予其良好的水溶性，同时可溶于二氯甲烷、DMF等常用有机溶剂。含对甲苯磺酸酯基团（良好离去基团）和叔丁氧羰基保护氨基，常温下呈无色至淡黄色黏稠液体或蜡状固体，需低温避光保存。
- 纯度
- ≥95%
- 储存条件
- -20°C低温避光密封保存
- 溶解性
- 溶于二氯甲烷、DMF、DMSO等有机溶剂，微溶于水
English description（英文原文，共 1262 字符）
Product Name:t-Boc-N-amido-PEG5-Tos
English Name:t-Boc-N-amido-PEG5-Tos
CAS No.:1404111-69-8
Aliases:t-Boc-N-amido-PEG5-Tos, Boc-NH-PEG5-Tos, tert-butyloxycarbonyl-PEG5-tosylate
Molecular Formula:C22H37NO9S
Physical Properties:This product is a hydrophilic PEG derivative. The pentaethylene glycol chain provides good water solubility, while it is also soluble in common organic solvents such as dichloromethane and DMF. It contains a tosylate group (excellent leaving group) and a tert-butyloxycarbonyl-protected amine. It appears as a colorless to pale yellow viscous liquid or waxy solid at room temperature, and should be stored at low temperature away from light.
Uses:Used as a key intermediate in drug conjugation, biomolecular modification, and PROTAC construction. The tosylate group enables nucleophilic substitution reactions to attach functional molecules to the PEG spacer, while the Boc group can be removed under mild acidic conditions to release a free amine for further conjugation.
Technical Specifications:
Purity: ≥95%
Molecular weight: 491.60
Molecular formula: C22H37NO9S
Storage: store sealed at -20°C, protected from light
Solubility: soluble in dichloromethane, DMF, DMSO and other organic solvents; slightly soluble in water
English Name:t-Boc-N-amido-PEG5-Tos
CAS No.:1404111-69-8
Aliases:t-Boc-N-amido-PEG5-Tos, Boc-NH-PEG5-Tos, tert-butyloxycarbonyl-PEG5-tosylate
Molecular Formula:C22H37NO9S
Physical Properties:This product is a hydrophilic PEG derivative. The pentaethylene glycol chain provides good water solubility, while it is also soluble in common organic solvents such as dichloromethane and DMF. It contains a tosylate group (excellent leaving group) and a tert-butyloxycarbonyl-protected amine. It appears as a colorless to pale yellow viscous liquid or waxy solid at room temperature, and should be stored at low temperature away from light.
Uses:Used as a key intermediate in drug conjugation, biomolecular modification, and PROTAC construction. The tosylate group enables nucleophilic substitution reactions to attach functional molecules to the PEG spacer, while the Boc group can be removed under mild acidic conditions to release a free amine for further conjugation.
Technical Specifications:
Purity: ≥95%
Molecular weight: 491.60
Molecular formula: C22H37NO9S
Storage: store sealed at -20°C, protected from light
Solubility: soluble in dichloromethane, DMF, DMSO and other organic solvents; slightly soluble in water
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常见问题
- N-叔丁氧羰基-五聚乙二醇-对甲苯磺酸酯的 CAS 号是多少？
- N-叔丁氧羰基-五聚乙二醇-对甲苯磺酸酯的 CAS 号是 1404111-69-8。
- N-叔丁氧羰基-五聚乙二醇-对甲苯磺酸酯的分子式和分子量是什么？
- N-叔丁氧羰基-五聚乙二醇-对甲苯磺酸酯的分子式为 C22H37NO9S，分子量约 491.60。
- N-叔丁氧羰基-五聚乙二醇-对甲苯磺酸酯的英文名称是什么？
- N-叔丁氧羰基-五聚乙二醇-对甲苯磺酸酯的英文名称为 t-Boc-N-amido-PEG5-Tos。
- N-叔丁氧羰基-五聚乙二醇-对甲苯磺酸酯还有哪些别名？
- N-叔丁氧羰基-五聚乙二醇-对甲苯磺酸酯又称 t-Boc-N-amido-PEG5-Tos、Boc-NH-PEG5-Tos、叔丁氧羰基五聚乙二醇对甲苯磺酸酯。
- N-叔丁氧羰基-五聚乙二醇-对甲苯磺酸酯有哪些供应商和生产厂家？
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