盐酸伊伐布雷定 (CAS No.148849-67-6)
- 物化性质
- 本品为白色或类白色结晶性粉末，无臭，味苦。在水中略溶，在甲醇中溶解，在乙醇中微溶，在乙醚中几乎不溶。熔点约为248℃（分解）。
- 技术参数
- 含量（按干燥品计）98.0%～102.0% 干燥失重 ≤0.5% 灼烧残渣 ≤0.1% 单一杂质 ≤0.1%，总杂质 ≤0.5% 重金属 ≤10ppm
English description（英文原文，共 1048 字符）
Product Name:Ivabradine hydrochloride
English Name:Ivabradine hydrochloride
CAS No.:148849-67-6
Aliases:Ivabradine HCl, Ivabradine hydrochloride salt
Molecular Formula:C27H37ClN2O5
Physical Properties:This product is a white to off-white crystalline powder, odorless and bitter in taste. It is slightly soluble in water, soluble in methanol, sparingly soluble in ethanol, and practically insoluble in diethyl ether. Melting point is approximately 248°C (decomposition).
Uses:Ivabradine hydrochloride is a specific hyperpolarization-activated cyclic nucleotide-gated channel (HCN) blocker that selectively inhibits the pacemaker current If of the sinoatrial node, thereby reducing heart rate. It is mainly used for the treatment of chronic stable angina pectoris and chronic heart failure in patients with contraindications or intolerance to beta-blockers.
Technical Specifications:
Assay (on dried basis): 98.0%–102.0%
Loss on drying: ≤0.5%
Residue on ignition: ≤0.1%
Single impurity: ≤0.1%; total impurities: ≤0.5%
Heavy metals: ≤10ppm
English Name:Ivabradine hydrochloride
CAS No.:148849-67-6
Aliases:Ivabradine HCl, Ivabradine hydrochloride salt
Molecular Formula:C27H37ClN2O5
Physical Properties:This product is a white to off-white crystalline powder, odorless and bitter in taste. It is slightly soluble in water, soluble in methanol, sparingly soluble in ethanol, and practically insoluble in diethyl ether. Melting point is approximately 248°C (decomposition).
Uses:Ivabradine hydrochloride is a specific hyperpolarization-activated cyclic nucleotide-gated channel (HCN) blocker that selectively inhibits the pacemaker current If of the sinoatrial node, thereby reducing heart rate. It is mainly used for the treatment of chronic stable angina pectoris and chronic heart failure in patients with contraindications or intolerance to beta-blockers.
Technical Specifications:
Assay (on dried basis): 98.0%–102.0%
Loss on drying: ≤0.5%
Residue on ignition: ≤0.1%
Single impurity: ≤0.1%; total impurities: ≤0.5%
Heavy metals: ≤10ppm
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常见问题
- 盐酸伊伐布雷定的 CAS 号是多少？
- 盐酸伊伐布雷定的 CAS 号是 148849-67-6。
- 盐酸伊伐布雷定的分子式和分子量是什么？
- 盐酸伊伐布雷定的分子式为 C27H37ClN2O5。
- 盐酸伊伐布雷定的英文名称是什么？
- 盐酸伊伐布雷定的英文名称为 Ivabradine hydrochloride。
- 盐酸伊伐布雷定还有哪些别名？
- 盐酸伊伐布雷定又称 伊伐布雷定盐酸盐、盐酸伊伐布雷定。
- 盐酸伊伐布雷定有哪些供应商和生产厂家？
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