N2-[芴甲氧羰基]-N6-[N-(1-氧代十六烷基)-L-GAMMA-谷氨酰]-L-赖氨酸 1'-叔丁酯 (14911 (CAS No.1491158-62-3)
![N2-[芴甲氧羰基]-N6-[N-(1-氧代十六烷基)-L-GAMMA-谷氨酰]-L-赖氨酸 1'-叔丁酯 (14911 1491158-62-3](/media/business/intermediate_covers/mid_27154.png)
- 中文别名
- Fmoc-Lys(棕榈酰-γ-谷氨酰)-叔丁酯；Fmoc-Lys(palmitoyl-γ-Glu)-OtBu
- 英文名称
- N2-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N6-[N-(1-oxohexadecyl)-L-γ-glutamyl]-L-lysine 1'-(tert-butyl) ester
- 分子式
- C42H63N3O7
- InChIKey
- LQQXBYSAGYOQJW-ZAQUEYBZSA-N
- 所属类别
- 中间体
- 物化性质
- 白色至类白色固体，可溶于二氯甲烷、N,N-二甲基甲酰胺等有机溶剂。为含有芴甲氧羰基(Fmoc)保护基和叔丁酯保护的赖氨酸衍生物，结构中含棕榈酰谷氨酰侧链，具有长链脂肪酰基的疏水性特征。
- 纯度
- ≥95% (HPLC)
- 外观
- 白色至类白色固体粉末
- 溶解性
- 溶于DCM、DMF、DMSO，微溶于甲醇和乙腈
- 储存条件
- -20℃避光、干燥密封保存
English description（英文原文，共 1567 字符）
Product Name:N2-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N6-[N-(1-oxohexadecyl)-L-γ-glutamyl]-L-lysine 1'-(tert-butyl) ester
English Name:N2-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N6-[N-(1-oxohexadecyl)-L-γ-glutamyl]-L-lysine 1'-(tert-butyl) ester
CAS No.:1491158-62-3
Aliases:Fmoc-Lys(palmitoyl-γ-glutamyl)-tert-butyl ester, Fmoc-Lys(Pal-γ-Glu)-OtBu
Molecular Formula:C42H63N3O7
Physical Properties:White to off-white solid, soluble in organic solvents such as dichloromethane and N,N-dimethylformamide. It is a lysine derivative bearing a fluorenylmethoxycarbonyl (Fmoc) protective group and a tert-butyl ester, with a palmitoyl-glutamyl side chain conferring hydrophobic long-chain fatty acyl characteristics.
Uses:This compound is an Fmoc-protected lysine derivative containing a palmitoyl-γ-glutamyl side chain, commonly used as a lipidated amino acid building block in solid-phase peptide synthesis. It is employed in the preparation of lipopeptides, fatty acid-modified peptides, and bioactive peptide conjugates with membrane affinity or self-assembly properties. The Fmoc group can be removed under mild basic conditions, while the tert-butyl ester can be selectively cleaved under acidic conditions, making it suitable for orthogonal peptide assembly strategies.
Technical Specifications:
Molecular formula: C42H63N3O7, molecular weight: 721.97
Purity: ≥95% (HPLC)
Appearance: white to off-white solid powder
Solubility: soluble in DCM, DMF, DMSO; slightly soluble in methanol and acetonitrile
Storage: store at -20°C, protected from light, sealed and dry
English Name:N2-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N6-[N-(1-oxohexadecyl)-L-γ-glutamyl]-L-lysine 1'-(tert-butyl) ester
CAS No.:1491158-62-3
Aliases:Fmoc-Lys(palmitoyl-γ-glutamyl)-tert-butyl ester, Fmoc-Lys(Pal-γ-Glu)-OtBu
Molecular Formula:C42H63N3O7
Physical Properties:White to off-white solid, soluble in organic solvents such as dichloromethane and N,N-dimethylformamide. It is a lysine derivative bearing a fluorenylmethoxycarbonyl (Fmoc) protective group and a tert-butyl ester, with a palmitoyl-glutamyl side chain conferring hydrophobic long-chain fatty acyl characteristics.
Uses:This compound is an Fmoc-protected lysine derivative containing a palmitoyl-γ-glutamyl side chain, commonly used as a lipidated amino acid building block in solid-phase peptide synthesis. It is employed in the preparation of lipopeptides, fatty acid-modified peptides, and bioactive peptide conjugates with membrane affinity or self-assembly properties. The Fmoc group can be removed under mild basic conditions, while the tert-butyl ester can be selectively cleaved under acidic conditions, making it suitable for orthogonal peptide assembly strategies.
Technical Specifications:
Molecular formula: C42H63N3O7, molecular weight: 721.97
Purity: ≥95% (HPLC)
Appearance: white to off-white solid powder
Solubility: soluble in DCM, DMF, DMSO; slightly soluble in methanol and acetonitrile
Storage: store at -20°C, protected from light, sealed and dry
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常见问题
- N2-[芴甲氧羰基]-N6-[N-(1-氧代十六烷基)-L-GAMMA-谷氨酰]-L-赖氨酸 1'-叔丁酯 (14911的 CAS 号是多少？
- N2-[芴甲氧羰基]-N6-[N-(1-氧代十六烷基)-L-GAMMA-谷氨酰]-L-赖氨酸 1'-叔丁酯 (14911的 CAS 号是 1491158-62-3。
- N2-[芴甲氧羰基]-N6-[N-(1-氧代十六烷基)-L-GAMMA-谷氨酰]-L-赖氨酸 1'-叔丁酯 (14911的分子式和分子量是什么？
- N2-[芴甲氧羰基]-N6-[N-(1-氧代十六烷基)-L-GAMMA-谷氨酰]-L-赖氨酸 1'-叔丁酯 (14911的分子式为 C42H63N3O7。
- N2-[芴甲氧羰基]-N6-[N-(1-氧代十六烷基)-L-GAMMA-谷氨酰]-L-赖氨酸 1'-叔丁酯 (14911的英文名称是什么？
- N2-[芴甲氧羰基]-N6-[N-(1-氧代十六烷基)-L-GAMMA-谷氨酰]-L-赖氨酸 1'-叔丁酯 (14911的英文名称为 N2-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N6-[N-(1-oxohexadecyl)-L-γ-glutamyl]-L-lysine 1'-(tert-butyl) ester。
- N2-[芴甲氧羰基]-N6-[N-(1-氧代十六烷基)-L-GAMMA-谷氨酰]-L-赖氨酸 1'-叔丁酯 (14911还有哪些别名？
- N2-[芴甲氧羰基]-N6-[N-(1-氧代十六烷基)-L-GAMMA-谷氨酰]-L-赖氨酸 1'-叔丁酯 (14911又称 Fmoc-Lys(棕榈酰-γ-谷氨酰)-叔丁酯、Fmoc-Lys(palmitoyl-γ-Glu)-OtBu。
- N2-[芴甲氧羰基]-N6-[N-(1-氧代十六烷基)-L-GAMMA-谷氨酰]-L-赖氨酸 1'-叔丁酯 (14911有哪些供应商和生产厂家？
- 掌上化工当前收录 1 条N2-[芴甲氧羰基]-N6-[N-(1-氧代十六烷基)-L-GAMMA-谷氨酰]-L-赖氨酸 1'-叔丁酯 (14911供应报价，来自 1 家供应商，可按地区、纯度、级别筛选对比。
- N2-[芴甲氧羰基]-N6-[N-(1-氧代十六烷基)-L-GAMMA-谷氨酰]-L-赖氨酸 1'-叔丁酯 (14911的供应商主要分布在哪些地区？
- N2-[芴甲氧羰基]-N6-[N-(1-氧代十六烷基)-L-GAMMA-谷氨酰]-L-赖氨酸 1'-叔丁酯 (14911的供应商主要分布在 上海市（1 条） 等地。
- N2-[芴甲氧羰基]-N6-[N-(1-氧代十六烷基)-L-GAMMA-谷氨酰]-L-赖氨酸 1'-叔丁酯 (14911有哪些级别可选？
- 平台上N2-[芴甲氧羰基]-N6-[N-(1-氧代十六烷基)-L-GAMMA-谷氨酰]-L-赖氨酸 1'-叔丁酯 (14911的供应级别包括 工业级。
- N2-[芴甲氧羰基]-N6-[N-(1-氧代十六烷基)-L-GAMMA-谷氨酰]-L-赖氨酸 1'-叔丁酯 (14911的报价单位是什么？
- N2-[芴甲氧羰基]-N6-[N-(1-氧代十六烷基)-L-GAMMA-谷氨酰]-L-赖氨酸 1'-叔丁酯 (14911的报价单位主要有 千克。
- 哪里可以查到N2-[芴甲氧羰基]-N6-[N-(1-氧代十六烷基)-L-GAMMA-谷氨酰]-L-赖氨酸 1'-叔丁酯 (14911的价格？
- 掌上化工N2-[芴甲氧羰基]-N6-[N-(1-氧代十六烷基)-L-GAMMA-谷氨酰]-L-赖氨酸 1'-叔丁酯 (14911产品页汇总了各供应商的最新报价与规格，地址：/chemicals/1491158-62-3/。部分供应商价格为电议，可通过页面上的询价功能直接获取。
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