1-乙酰氧基-2,5-二氧代吡咯烷-3-磺酸 (CAS No.152305-87-8)
- 中文别名
- 磺基琥珀酰亚胺乙酸酯；磺基-NHS-乙酸酯；乙酸磺基琥珀酰亚胺酯；磺酸基-活性脂-乙酸
- 英文名称
- Sulfo-NHS-Acetate
- 分子式
- C6H6NNaO7S
- 分子量
- 259.2
- 所属类别
- 试剂实验设备
- 物化性质
- 白色至类白色固体粉末，易吸潮，水溶性良好。本品为水溶性NHS酯类酰化试剂，结构中含有亲水性磺酸基钠盐，在水溶液中可缓慢水解，随水解程度增加酰化活性逐渐降低；需避光、防潮、低温保存。
- 纯度
- ≥90%（HPLC），高纯度批次可达98%以上
- 性状
- 固体粉末
- 溶解性
- 易溶于水
- 储存条件
- -20℃避光、干燥保存，避免反复冻融
English description（英文原文，共 1390 字符）
Product Name:Sulfo-NHS-Acetate
English Name:Sulfo-NHS-Acetate
CAS No.:152305-87-8
Aliases:Sulfosuccinimidyl acetate, Acetic acid sulfosuccinimide ester, Sodium 1-acetoxy-2,5-dioxopyrrolidine-3-sulfonate, Sulfo-NHS-acetate
Molecular Formula:C6H6NNaO7S
Physical Properties:White to off-white solid powder, hygroscopic, readily soluble in water. It is a water-soluble NHS ester acylation reagent containing a hydrophilic sulfonate sodium salt. It hydrolyzes slowly in aqueous solution, and the acylation activity gradually decreases with hydrolysis; store away from light and moisture at low temperature.
Uses:A water-soluble NHS ester acylation reagent that irreversibly reacts with primary amine groups (e.g., lysine ε-amino groups) at pH above 7 to introduce acetyl groups into target molecules. It is commonly used to block primary amines before protein crosslinking to prevent protein self-polymerization. It is also applied to inhibit polymerization during conjugation of hapten peptides to carrier proteins for immunogen preparation, and serves as an amine-blocking agent in bioconjugation and labeling experiments.
Technical Specifications:
Purity: ≥90% by HPLC; high-purity batches up to ≥98%
Molecular weight: 259.2
Appearance: solid powder
Solubility: readily soluble in water
Storage: store at -20°C, protected from light and moisture; avoid repeated freeze-thaw cycles
English Name:Sulfo-NHS-Acetate
CAS No.:152305-87-8
Aliases:Sulfosuccinimidyl acetate, Acetic acid sulfosuccinimide ester, Sodium 1-acetoxy-2,5-dioxopyrrolidine-3-sulfonate, Sulfo-NHS-acetate
Molecular Formula:C6H6NNaO7S
Physical Properties:White to off-white solid powder, hygroscopic, readily soluble in water. It is a water-soluble NHS ester acylation reagent containing a hydrophilic sulfonate sodium salt. It hydrolyzes slowly in aqueous solution, and the acylation activity gradually decreases with hydrolysis; store away from light and moisture at low temperature.
Uses:A water-soluble NHS ester acylation reagent that irreversibly reacts with primary amine groups (e.g., lysine ε-amino groups) at pH above 7 to introduce acetyl groups into target molecules. It is commonly used to block primary amines before protein crosslinking to prevent protein self-polymerization. It is also applied to inhibit polymerization during conjugation of hapten peptides to carrier proteins for immunogen preparation, and serves as an amine-blocking agent in bioconjugation and labeling experiments.
Technical Specifications:
Purity: ≥90% by HPLC; high-purity batches up to ≥98%
Molecular weight: 259.2
Appearance: solid powder
Solubility: readily soluble in water
Storage: store at -20°C, protected from light and moisture; avoid repeated freeze-thaw cycles
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常见问题
- 1-乙酰氧基-2,5-二氧代吡咯烷-3-磺酸的 CAS 号是多少？
- 1-乙酰氧基-2,5-二氧代吡咯烷-3-磺酸的 CAS 号是 152305-87-8。
- 1-乙酰氧基-2,5-二氧代吡咯烷-3-磺酸的分子式和分子量是什么？
- 1-乙酰氧基-2,5-二氧代吡咯烷-3-磺酸的分子式为 C6H6NNaO7S，分子量约 259.2。
- 1-乙酰氧基-2,5-二氧代吡咯烷-3-磺酸的英文名称是什么？
- 1-乙酰氧基-2,5-二氧代吡咯烷-3-磺酸的英文名称为 Sulfo-NHS-Acetate。
- 1-乙酰氧基-2,5-二氧代吡咯烷-3-磺酸还有哪些别名？
- 1-乙酰氧基-2,5-二氧代吡咯烷-3-磺酸又称 磺基琥珀酰亚胺乙酸酯、磺基-NHS-乙酸酯、乙酸磺基琥珀酰亚胺酯、磺酸基-活性脂-乙酸。
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