利托那韦 (CAS No.155213-67-5)
- 物化性质
- 白色或类白色结晶性粉末,几乎不溶于水,易溶于甲醇、乙醇、二氯甲烷等有机溶剂。熔点约120-125℃,比旋度[α]D20为-16°至-20°(c=1, 甲醇),分子量约720.94。
- 技术参数
- 含量(HPLC)≥98.5% 水分≤1.0% 灼烧残渣≤0.1% 重金属≤20ppm
English description(英文原文,共 879 字符)
Product Name:Ritonavir
English Name:Ritonavir
CAS No.:155213-67-5
Aliases:ABT-538, RTV
Molecular Formula:C37H48N6O5S2
Physical Properties:White to off-white crystalline powder. Practically insoluble in water (<0.1 mg/mL), soluble in methanol, ethanol, dichloromethane and other organic solvents. Melting point approximately 120-125°C. Specific rotation [α]D20 is -16° to -20° (c=1, methanol). Molecular weight approximately 720.94.
Uses:Ritonavir is an HIV protease inhibitor used for the treatment of AIDS. It is often combined with other antiretroviral drugs to enhance antiviral efficacy. It also inhibits the CYP3A4 enzyme, improving the pharmacokinetic profile of other protease inhibitors.
Technical Specifications:
Content (HPLC) ≥98.5%
Water ≤1.0%
Residue on ignition ≤0.1%
Heavy metals ≤20ppm
Related substances: single impurity ≤0.5%, total impurities ≤2.0%
English Name:Ritonavir
CAS No.:155213-67-5
Aliases:ABT-538, RTV
Molecular Formula:C37H48N6O5S2
Physical Properties:White to off-white crystalline powder. Practically insoluble in water (<0.1 mg/mL), soluble in methanol, ethanol, dichloromethane and other organic solvents. Melting point approximately 120-125°C. Specific rotation [α]D20 is -16° to -20° (c=1, methanol). Molecular weight approximately 720.94.
Uses:Ritonavir is an HIV protease inhibitor used for the treatment of AIDS. It is often combined with other antiretroviral drugs to enhance antiviral efficacy. It also inhibits the CYP3A4 enzyme, improving the pharmacokinetic profile of other protease inhibitors.
Technical Specifications:
Content (HPLC) ≥98.5%
Water ≤1.0%
Residue on ignition ≤0.1%
Heavy metals ≤20ppm
Related substances: single impurity ≤0.5%, total impurities ≤2.0%
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常见问题
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- 利托那韦的 CAS 号是 155213-67-5。
- 利托那韦的分子式和分子量是什么?
- 利托那韦的分子式为 C37H48N6O5S2。
- 利托那韦的英文名称是什么?
- 利托那韦的英文名称为 Ritonavir。
- 利托那韦还有哪些别名?
- 利托那韦又称 ABT-538、RTV。
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