D-2-氯丙酰基-L-谷氨酰胺 (CAS No.159141-33-0)
- 中文别名
- N-(D-2-氯丙酰基)-L-谷氨酰胺
- 英文名称
- D-2-Chloropropionyl-L-glutamine
- 分子式
- C8H13ClN2O4
- 分子量
- 236.65
- 所属类别
- 试剂实验设备
- 物化性质
- 分子量236.65。白色至类白色结晶性粉末，无明显特殊气味。易溶于水、甲醇、乙醇等极性有机溶剂，微溶于丙酮、乙酸乙酯等中等极性溶剂，难溶于石油醚、正己烷等非极性溶剂。常温干燥条件下稳定，避免与强酸、强碱、强氧化剂接触；酰胺键在强酸或强碱条件下可发生水解，生成D-2-氯丙酸和L-谷氨酰胺；氯代烷基可发生亲核取代反应。具有两个手性中心，为非对映异构体纯品，旋光性数据无公开文献值，需通过手性色谱法测定。
- 纯度
- 分析纯
- 外观
- 白色至类白色结晶性粉末
- 溶解性
- 易溶于水、甲醇、乙醇，微溶于丙酮、乙酸乙酯，难溶于石油醚、正己烷
English description（英文原文，共 2276 字符）
Product Name:D-2-Chloropropionyl-L-glutamine
English Name:D-2-Chloropropionyl-L-glutamine
CAS No.:159141-33-0
Aliases:N-[(2R)-2-Chloropropanoyl]-L-glutamine
Molecular Formula:C8H13ClN2O4
Physical Properties:Molecular weight: 236.65. White to off-white crystalline powder with no obvious special odor. Readily soluble in polar organic solvents such as water, methanol, and ethanol; slightly soluble in medium-polarity solvents such as acetone and ethyl acetate; sparingly soluble in non-polar solvents such as petroleum ether and n-hexane. Stable under normal temperature and dry conditions; avoid contact with strong acids, strong bases, and strong oxidants. The amide bond can be hydrolyzed under strong acid or strong base conditions to give D-2-chloropropionic acid and L-glutamine; the chloroalkyl group can undergo nucleophilic substitution reactions. It possesses two chiral centers and is a diastereomerically pure compound; no literature value for optical rotation is available, and it should be determined by chiral chromatography.
Uses:Used as a chiral amide building block in organic synthesis, it enables the construction of various chiral compounds containing the D-2-chloropropionyl-L-glutamine skeleton via amide bond modification or nucleophilic substitution of the chloroalkyl group, serving as an important intermediate for complex chiral molecules. It is also employed in the synthesis of chiral polypeptide derivatives through condensation with other amino acids or peptide fragments to modulate their spatial structure and biological activity. In pharmaceutical research, it acts as a potential prodrug for activity screening, especially in the fields of enzyme inhibitors and receptor modulators. In scientific experiments, it serves as a model chiral amino acid derivative for studying the effects of chiral acylation on amino acid properties and reaction activity, as well as optimizing methods for separation and analysis of diastereomers.
Technical Specifications:
Molecular weight: 236.65
Purity: analytical pure
Appearance: white to off-white crystalline powder
Solubility: readily soluble in water, methanol, ethanol; slightly soluble in acetone, ethyl acetate; sparingly soluble in petroleum ether, n-hexane
Package specification: 25g
English Name:D-2-Chloropropionyl-L-glutamine
CAS No.:159141-33-0
Aliases:N-[(2R)-2-Chloropropanoyl]-L-glutamine
Molecular Formula:C8H13ClN2O4
Physical Properties:Molecular weight: 236.65. White to off-white crystalline powder with no obvious special odor. Readily soluble in polar organic solvents such as water, methanol, and ethanol; slightly soluble in medium-polarity solvents such as acetone and ethyl acetate; sparingly soluble in non-polar solvents such as petroleum ether and n-hexane. Stable under normal temperature and dry conditions; avoid contact with strong acids, strong bases, and strong oxidants. The amide bond can be hydrolyzed under strong acid or strong base conditions to give D-2-chloropropionic acid and L-glutamine; the chloroalkyl group can undergo nucleophilic substitution reactions. It possesses two chiral centers and is a diastereomerically pure compound; no literature value for optical rotation is available, and it should be determined by chiral chromatography.
Uses:Used as a chiral amide building block in organic synthesis, it enables the construction of various chiral compounds containing the D-2-chloropropionyl-L-glutamine skeleton via amide bond modification or nucleophilic substitution of the chloroalkyl group, serving as an important intermediate for complex chiral molecules. It is also employed in the synthesis of chiral polypeptide derivatives through condensation with other amino acids or peptide fragments to modulate their spatial structure and biological activity. In pharmaceutical research, it acts as a potential prodrug for activity screening, especially in the fields of enzyme inhibitors and receptor modulators. In scientific experiments, it serves as a model chiral amino acid derivative for studying the effects of chiral acylation on amino acid properties and reaction activity, as well as optimizing methods for separation and analysis of diastereomers.
Technical Specifications:
Molecular weight: 236.65
Purity: analytical pure
Appearance: white to off-white crystalline powder
Solubility: readily soluble in water, methanol, ethanol; slightly soluble in acetone, ethyl acetate; sparingly soluble in petroleum ether, n-hexane
Package specification: 25g
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常见问题
- D-2-氯丙酰基-L-谷氨酰胺的 CAS 号是多少？
- D-2-氯丙酰基-L-谷氨酰胺的 CAS 号是 159141-33-0。
- D-2-氯丙酰基-L-谷氨酰胺的分子式和分子量是什么？
- D-2-氯丙酰基-L-谷氨酰胺的分子式为 C8H13ClN2O4，分子量约 236.65。
- D-2-氯丙酰基-L-谷氨酰胺的英文名称是什么？
- D-2-氯丙酰基-L-谷氨酰胺的英文名称为 D-2-Chloropropionyl-L-glutamine。
- D-2-氯丙酰基-L-谷氨酰胺还有哪些别名？
- D-2-氯丙酰基-L-谷氨酰胺又称 N-(D-2-氯丙酰基)-L-谷氨酰胺。
- D-2-氯丙酰基-L-谷氨酰胺有哪些供应商和生产厂家？
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