6-(三氟甲基)吡嗪-2-甲酸甲酯 (CAS No.1644548-81-1)

Product Name:Methyl 6-(trifluoromethyl)pyrazine-2-carboxylate

English Name:Methyl 6-(trifluoromethyl)pyrazine-2-carboxylate

CAS No.:1644548-81-1

Aliases:Methyl 6-(trifluoromethyl)pyrazine-2-carboxylate, 2-(Trifluoromethyl)pyrazine-5-carboxylic acid methyl ester

Molecular Formula:C7H5F3N2O2

Physical Properties:This compound is a pyrazine-based fluorinated intermediate, typically appearing as a colorless to pale yellow liquid or low-melting solid. It contains a trifluoromethyl group and an ester group, with moderate polarity. It is readily soluble in organic solvents such as methanol, ethanol, and dichloromethane, but insoluble in water. The density is approximately 1.4 g/cm³, boiling point around 200°C, flash point around 85°C, and molecular weight 206.12.

Uses:It is used as a key intermediate in pharmaceutical and agrochemical synthesis, particularly for preparing pyrazine-based active molecules containing trifluoromethyl groups. The ester group can be further hydrolyzed to a carboxylic acid or reduced to an alcohol, enabling the construction of various heterocyclic compounds. It is also employed in the synthesis of functional materials.

Technical Specifications:

Molecular formula: C7H5F3N2O2, molecular weight: 206.12

Density: 1.4±0.1 g/cm³ (predicted)

Boiling point: approximately 200°C (predicted)

Flash point: approximately 85°C (predicted)

Storage conditions: keep sealed, protected from light, stored in a dry and cool place