6,7-二甲氧乙氧基喹唑啉-4-酮 (CAS No.179688-29-0)
- 物化性质
- 白色至类白色结晶性粉末,分子量294.30,熔点约190℃。微溶于水,溶于二甲基亚砜和N,N-二甲基甲酰胺,微溶于甲醇和乙醇。
- 外观
- 白色至类白色结晶性粉末
- 贮存条件
- 密封、避光、阴凉干燥处保存
English description(英文原文,共 1199 字符)
Product Name:6,7-Bis-(2-methoxyethoxy)-4(3H)-quinazolinone
English Name:6,7-Bis-(2-methoxyethoxy)-4(3H)-quinazolinone
CAS No.:179688-29-0
Aliases:6,7-Bis(2-methoxyethoxy)quinazolin-4-one, Erlotinib intermediate 3, Erlotinib intermediate 5, Erlotinib impurity E, Erlotinib lactam impurity
Molecular Formula:C14H18N2O5
Physical Properties:White to off-white crystalline powder, molecular weight 294.30, melting point approximately 190°C. Slightly soluble in water, soluble in dimethyl sulfoxide and N,N-dimethylformamide, sparingly soluble in methanol and ethanol.
Uses:This product is a key intermediate in the synthesis of erlotinib hydrochloride, an antineoplastic drug. Erlotinib is an epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor used clinically for the treatment of non-small cell lung cancer and pancreatic cancer. This product is also used as an impurity reference standard for the related substance testing of erlotinib.
Technical Specifications:
Assay (HPLC): ≥99.0%
Molecular formula: C14H18N2O5; Molecular weight: 294.30
Appearance: white to off-white crystalline powder
Loss on drying: ≤0.5%
Storage: keep sealed, protected from light, in a cool dry place
English Name:6,7-Bis-(2-methoxyethoxy)-4(3H)-quinazolinone
CAS No.:179688-29-0
Aliases:6,7-Bis(2-methoxyethoxy)quinazolin-4-one, Erlotinib intermediate 3, Erlotinib intermediate 5, Erlotinib impurity E, Erlotinib lactam impurity
Molecular Formula:C14H18N2O5
Physical Properties:White to off-white crystalline powder, molecular weight 294.30, melting point approximately 190°C. Slightly soluble in water, soluble in dimethyl sulfoxide and N,N-dimethylformamide, sparingly soluble in methanol and ethanol.
Uses:This product is a key intermediate in the synthesis of erlotinib hydrochloride, an antineoplastic drug. Erlotinib is an epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor used clinically for the treatment of non-small cell lung cancer and pancreatic cancer. This product is also used as an impurity reference standard for the related substance testing of erlotinib.
Technical Specifications:
Assay (HPLC): ≥99.0%
Molecular formula: C14H18N2O5; Molecular weight: 294.30
Appearance: white to off-white crystalline powder
Loss on drying: ≤0.5%
Storage: keep sealed, protected from light, in a cool dry place
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1 条供应报价
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常见问题
- 6,7-二甲氧乙氧基喹唑啉-4-酮的 CAS 号是多少?
- 6,7-二甲氧乙氧基喹唑啉-4-酮的 CAS 号是 179688-29-0。
- 6,7-二甲氧乙氧基喹唑啉-4-酮的分子式和分子量是什么?
- 6,7-二甲氧乙氧基喹唑啉-4-酮的分子式为 C14H18N2O5。
- 6,7-二甲氧乙氧基喹唑啉-4-酮的英文名称是什么?
- 6,7-二甲氧乙氧基喹唑啉-4-酮的英文名称为 6,7-Bis-(2-methoxyethoxy)-4(3H)-quinazolinone。
- 6,7-二甲氧乙氧基喹唑啉-4-酮还有哪些别名?
- 6,7-二甲氧乙氧基喹唑啉-4-酮又称 6,7-双(2-甲氧基乙氧基)喹唑啉-4-酮、埃罗替尼中间体3、埃罗替尼中间体5、盐酸埃罗替尼中间体五、厄洛替尼内酰胺杂质、埃罗替尼杂质 E。
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