4-(3-氯-4-氟苯基氨基)-7-甲氧基喹唑啉-6-基乙酸酯盐酸盐 (CAS No.184475-70-5)
- 中文别名
- 4-(3-氯-4-氟苯基氨基)-7-甲氧基-6-乙酰氧基喹唑啉盐酸盐；吉非替尼中间体；6-乙酰氧基-4-(3-氯-4-氟苯基氨基)-7-甲氧基喹唑啉盐酸盐
- 英文名称
- 4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-yl acetate hydrochloride
- 分子式
- C17H14Cl2FN3O3
- 分子量
- 398.21
- InChIKey
- RBFWFFFXYPQXHG-UHFFFAOYSA-N
- 所属类别
- 中间体
- 物化性质
- 白色至类白色结晶性粉末，溶于甲醇、乙醇、DMSO等有机溶剂，微溶于水。在空气中较稳定，但需避光、防潮保存。
- 技术参数
- 含量（HPLC）≥98%
- 外观
- 白色至类白色固体粉末
- 储存条件
- -20℃，避光、干燥保存
English description（英文原文，共 1169 字符）
Product Name:4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-yl acetate hydrochloride
English Name:4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-yl acetate hydrochloride
CAS No.:184475-70-5
Aliases:4-(3-Chloro-4-fluoroanilino)-7-methoxyquinazolin-6-yl acetate hydrochloride, Gefitinib intermediate, 6-acetoxy-4-(3-chloro-4-fluorophenylamino)-7-methoxyquinazoline hydrochloride
Molecular Formula:C17H14Cl2FN3O3
Physical Properties:White to off-white crystalline powder. Soluble in methanol, ethanol, DMSO and other organic solvents; slightly soluble in water. Stable in air, but store protected from light and moisture.
Uses:This product is a key intermediate in the synthesis of gefitinib, a quinazoline-based EGFR inhibitor precursor, mainly used in the development and production of anticancer drugs. In chemical synthesis, it is used as starting material or intermediate, and after deprotection it generates the active hydroxyquinazoline derivative.
Technical Specifications:
Purity (HPLC): ≥98%
Appearance: white to off-white solid powder
Molecular weight: 398.21
Water content: ≤0.5%
Storage: at -20°C, protected from light and kept dry
English Name:4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-yl acetate hydrochloride
CAS No.:184475-70-5
Aliases:4-(3-Chloro-4-fluoroanilino)-7-methoxyquinazolin-6-yl acetate hydrochloride, Gefitinib intermediate, 6-acetoxy-4-(3-chloro-4-fluorophenylamino)-7-methoxyquinazoline hydrochloride
Molecular Formula:C17H14Cl2FN3O3
Physical Properties:White to off-white crystalline powder. Soluble in methanol, ethanol, DMSO and other organic solvents; slightly soluble in water. Stable in air, but store protected from light and moisture.
Uses:This product is a key intermediate in the synthesis of gefitinib, a quinazoline-based EGFR inhibitor precursor, mainly used in the development and production of anticancer drugs. In chemical synthesis, it is used as starting material or intermediate, and after deprotection it generates the active hydroxyquinazoline derivative.
Technical Specifications:
Purity (HPLC): ≥98%
Appearance: white to off-white solid powder
Molecular weight: 398.21
Water content: ≤0.5%
Storage: at -20°C, protected from light and kept dry
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常见问题
- 4-(3-氯-4-氟苯基氨基)-7-甲氧基喹唑啉-6-基乙酸酯盐酸盐的 CAS 号是多少？
- 4-(3-氯-4-氟苯基氨基)-7-甲氧基喹唑啉-6-基乙酸酯盐酸盐的 CAS 号是 184475-70-5。
- 4-(3-氯-4-氟苯基氨基)-7-甲氧基喹唑啉-6-基乙酸酯盐酸盐的分子式和分子量是什么？
- 4-(3-氯-4-氟苯基氨基)-7-甲氧基喹唑啉-6-基乙酸酯盐酸盐的分子式为 C17H14Cl2FN3O3，分子量约 398.21。
- 4-(3-氯-4-氟苯基氨基)-7-甲氧基喹唑啉-6-基乙酸酯盐酸盐的英文名称是什么？
- 4-(3-氯-4-氟苯基氨基)-7-甲氧基喹唑啉-6-基乙酸酯盐酸盐的英文名称为 4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-yl acetate hydrochloride。
- 4-(3-氯-4-氟苯基氨基)-7-甲氧基喹唑啉-6-基乙酸酯盐酸盐还有哪些别名？
- 4-(3-氯-4-氟苯基氨基)-7-甲氧基喹唑啉-6-基乙酸酯盐酸盐又称 4-(3-氯-4-氟苯基氨基)-7-甲氧基-6-乙酰氧基喹唑啉盐酸盐、吉非替尼中间体、6-乙酰氧基-4-(3-氯-4-氟苯基氨基)-7-甲氧基喹唑啉盐酸盐。
- 4-(3-氯-4-氟苯基氨基)-7-甲氧基喹唑啉-6-基乙酸酯盐酸盐有哪些供应商和生产厂家？
- 掌上化工当前收录 1 条4-(3-氯-4-氟苯基氨基)-7-甲氧基喹唑啉-6-基乙酸酯盐酸盐供应报价，来自 1 家供应商，可按地区、纯度、级别筛选对比。
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- 4-(3-氯-4-氟苯基氨基)-7-甲氧基喹唑啉-6-基乙酸酯盐酸盐的供应商主要分布在 上海市（1 条） 等地。
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- 平台上4-(3-氯-4-氟苯基氨基)-7-甲氧基喹唑啉-6-基乙酸酯盐酸盐的供应级别包括 工业级。
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