那他珠单抗 (CAS No.189261-10-7)
- 物化性质
- 重组人源化IgG4单克隆抗体，分子量约149 kDa。为无色至淡黄色澄明液体，可略带乳光，溶于水，不可溶于有机溶剂。pH值约6.5~7.4，于2~8°C避光保存，不可冷冻。
- 技术参数
- 本品为无菌注射剂，蛋白浓度约20 mg/mL。 单次使用剂量通常为300 mg，经静脉输注给药。 储存条件为2~8°C避光保存，避免冷冻和剧烈震荡。 pH值约为6.5~7.4，渗透压接近生理等渗范围。
English description（英文原文，共 1138 字符）
Product Name:Natalizumab
English Name:Natalizumab
CAS No.:189261-10-7
Aliases:Natalizumab, Antegren, Tysabri
Physical Properties:Recombinant humanized IgG4 monoclonal antibody with a molecular weight of approximately 149 kDa. It appears as a colorless to pale yellow clear liquid, possibly slightly opalescent, soluble in water and insoluble in organic solvents. The pH is approximately 6.5–7.4. Store at 2–8°C protected from light; do not freeze.
Uses:Natalizumab is an α4 integrin antagonist that inhibits the migration of inflammatory cells into the central nervous system and intestines. It is used for the treatment of relapsing forms of multiple sclerosis and moderately to severely active Crohn's disease, reducing relapse rates and improving clinical symptoms.
Technical Specifications:
Sterile injection solution with a protein concentration of approximately 20 mg/mL.
Single-use dose is typically 300 mg, administered by intravenous infusion.
Storage conditions: keep at 2–8°C, protected from light, do not freeze or shake vigorously.
pH is approximately 6.5–7.4, with osmolality close to physiological isotonic range.
English Name:Natalizumab
CAS No.:189261-10-7
Aliases:Natalizumab, Antegren, Tysabri
Physical Properties:Recombinant humanized IgG4 monoclonal antibody with a molecular weight of approximately 149 kDa. It appears as a colorless to pale yellow clear liquid, possibly slightly opalescent, soluble in water and insoluble in organic solvents. The pH is approximately 6.5–7.4. Store at 2–8°C protected from light; do not freeze.
Uses:Natalizumab is an α4 integrin antagonist that inhibits the migration of inflammatory cells into the central nervous system and intestines. It is used for the treatment of relapsing forms of multiple sclerosis and moderately to severely active Crohn's disease, reducing relapse rates and improving clinical symptoms.
Technical Specifications:
Sterile injection solution with a protein concentration of approximately 20 mg/mL.
Single-use dose is typically 300 mg, administered by intravenous infusion.
Storage conditions: keep at 2–8°C, protected from light, do not freeze or shake vigorously.
pH is approximately 6.5–7.4, with osmolality close to physiological isotonic range.
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常见问题
- 那他珠单抗的 CAS 号是多少？
- 那他珠单抗的 CAS 号是 189261-10-7。
- 那他珠单抗的英文名称是什么？
- 那他珠单抗的英文名称为 Natalizumab。
- 那他珠单抗还有哪些别名？
- 那他珠单抗又称 Natalizumab、Antegren、Tysabri。
- 那他珠单抗有哪些供应商和生产厂家？
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