E3连接酶配体1A (CAS No.1948273-02-6)
- 物化性质
- 白色至类白色固体。可溶于DMSO、DMF和甲醇,微溶于水。分子量444.59。建议在-20℃、惰性气体保护下避光密封保存。
- 纯度
- ≥95%
- 储存条件
- -20℃冷冻、避光、惰性气体保护密封保存
English description(英文原文,共 1098 字符)
Product Name:E3 Ligase Ligand 1A
English Name:E3 Ligase Ligand 1A
CAS No.:1948273-02-6
Aliases:(S,R,S)-AHPC-ME (VHL Ligand 2), E3 ubiquitin ligase ligand 1A, (2S,4R)-1-((S)-2-amino-3,3-dimethylbutanoyl)-4-hydroxy-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide
Molecular Formula:C23H32N4O3S
Physical Properties:White to off-white solid. Soluble in DMSO, DMF, and methanol; sparingly soluble in water. Molecular weight: 444.59. Recommended storage: sealed and stored at -20°C under inert gas, protected from light.
Uses:E3 Ligase Ligand 1A is a VHL E3 ubiquitin ligase ligand and a core component of PROTAC (proteolysis-targeting chimera) technology. It is used to design and synthesize PROTAC molecules for targeted protein degradation, with broad applications in targeted cancer therapy and related drug discovery.
Technical Specifications:
Purity: ≥95%
Molecular formula: C23H32N4O3S
Molecular weight: 444.59
Packaging: 1g, 5g, 25g, 100g, 500g (customized packaging available)
Storage: store at -20°C in a freezer, protected from light, sealed under inert gas
English Name:E3 Ligase Ligand 1A
CAS No.:1948273-02-6
Aliases:(S,R,S)-AHPC-ME (VHL Ligand 2), E3 ubiquitin ligase ligand 1A, (2S,4R)-1-((S)-2-amino-3,3-dimethylbutanoyl)-4-hydroxy-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide
Molecular Formula:C23H32N4O3S
Physical Properties:White to off-white solid. Soluble in DMSO, DMF, and methanol; sparingly soluble in water. Molecular weight: 444.59. Recommended storage: sealed and stored at -20°C under inert gas, protected from light.
Uses:E3 Ligase Ligand 1A is a VHL E3 ubiquitin ligase ligand and a core component of PROTAC (proteolysis-targeting chimera) technology. It is used to design and synthesize PROTAC molecules for targeted protein degradation, with broad applications in targeted cancer therapy and related drug discovery.
Technical Specifications:
Purity: ≥95%
Molecular formula: C23H32N4O3S
Molecular weight: 444.59
Packaging: 1g, 5g, 25g, 100g, 500g (customized packaging available)
Storage: store at -20°C in a freezer, protected from light, sealed under inert gas
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常见问题
- E3连接酶配体1A的 CAS 号是多少?
- E3连接酶配体1A的 CAS 号是 1948273-02-6。
- E3连接酶配体1A的分子式和分子量是什么?
- E3连接酶配体1A的分子式为 C23H32N4O3S,分子量约 444.59。
- E3连接酶配体1A的英文名称是什么?
- E3连接酶配体1A的英文名称为 E3 Ligase Ligand 1A。
- E3连接酶配体1A还有哪些别名?
- E3连接酶配体1A又称 (S,R,S)-AHPC-ME (VHL配体2)、E3泛素连接酶配体1A、(2S,4R)-1-((S)-2-氨基-3,3-二甲基丁酰基)-4-羟基-N-((S)-1-(4-(4-甲基噻唑-5-基)苯基)乙基)吡咯烷-2-甲酰胺。
- E3连接酶配体1A有哪些供应商和生产厂家?
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