4-(4,6-二甲氧基三嗪-2-基)-4-甲基吗啉盐酸盐 (CAS No.3945-69-5)

Product Name:4-(4,6-Dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride

English Name:4-(4,6-Dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride

CAS No.:3945-69-5

Aliases:DMTMM chloride, 2-(4-methylmorpholin-4-ium-4-yl)-4,6-dimethoxy-1,3,5-triazine chloride, 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholin-4-ium chloride

Molecular Formula:C10H19ClN4O4

Physical Properties:White to off-white crystalline powder with a molecular weight of 294.74 and a melting range of approximately 185-190°C. Freely soluble in polar solvents such as water, methanol, ethanol, and dimethylformamide; slightly soluble in dichloromethane and ethyl acetate. Relatively stable in air but should be sealed and stored away from moisture. As a quaternary ammonium salt condensing agent, its aqueous solution is weakly acidic.

Uses:Used as a novel condensing reagent in peptide synthesis, serving as a mild alternative to carbodiimide-type coupling agents (e.g., DCC, EDC). Widely applied in amidation of carboxylic acids with amines and in esterification reactions, achieving efficient coupling in either aqueous or organic phases, particularly suitable for substrates bearing sensitive functional groups. Also employed in solid-phase peptide synthesis to minimize racemization.

Technical Specifications:

Purity ≥ 97%

White to off-white crystalline powder

Loss on drying ≤ 1.0%

Melting range 185-190°C

Packaged in 25 kg/drum; store in a cool, dry place