醋酸氟氢可的松 (CAS No.514-36-3)
- 中文别名
- 9α-氟氢可的松；9α-氟皮质醇；氟可的索；9α-氟可的索；氟氢可的松；9α-氟皮质醇醋酸酯；9α-氟醋酸氢化可的松
- 英文名称
- Fludrocortisone Acetate
- 分子式
- C23H31FO6
- InChIKey
- SYWHXTATXSMDSB-GSLJADNHSA-N
- 所属类别
- 中间体
- 物化性质
- 白色或类白色结晶性粉末，无臭，味微苦。在乙醇、丙酮或氯仿中易溶，在水中不溶。熔点约为190-194℃（分解）。具有旋光性，比旋光度约+128°（二氧六环中）。在空气中稳定，遇光易变色。
- 技术参数
- 含量（C23H31FO6）按干燥品计算应为97.0%-102.0% 比旋光度为+125°至+132°（1%二氧六环溶液，20℃） 干燥失重不得过1.0% 重金属含量不得过20ppm 炽灼残渣不得过0.1%
English description（英文原文，共 1276 字符）
Product Name:Fludrocortisone Acetate
English Name:Fludrocortisone Acetate
CAS No.:514-36-3
Aliases:9α-Fluorohydrocortisone, 9α-Fluorocortisol, Fluorcortisone, 9α-Fluorocortisone Acetate
Molecular Formula:C23H31FO6
Physical Properties:White or off-white crystalline powder, odorless, with a slightly bitter taste. Freely soluble in ethanol, acetone, or chloroform; insoluble in water. Melting point approximately 190-194°C (decomposition). Optically active, specific rotation approximately +128° (in dioxane). Stable in air, discolors upon exposure to light.
Uses:Primarily used topically for the treatment of skin conditions including contact dermatitis, eczema, and neurodermatitis, providing significant anti-inflammatory, anti-allergic, and antipruritic effects. As an adrenocortical hormone drug with both glucocorticoid and mineralocorticoid activity, it is also used for replacement therapy in adrenocortical insufficiency and as adjunctive treatment for salt-losing congenital adrenal hyperplasia.
Technical Specifications:
Assay (C23H31FO6, on dried basis) is 97.0%-102.0%
Specific rotation is +125° to +132° (1% solution in dioxane, 20°C)
Loss on drying is not more than 1.0%
Heavy metals are not more than 20 ppm
Residue on ignition is not more than 0.1%
English Name:Fludrocortisone Acetate
CAS No.:514-36-3
Aliases:9α-Fluorohydrocortisone, 9α-Fluorocortisol, Fluorcortisone, 9α-Fluorocortisone Acetate
Molecular Formula:C23H31FO6
Physical Properties:White or off-white crystalline powder, odorless, with a slightly bitter taste. Freely soluble in ethanol, acetone, or chloroform; insoluble in water. Melting point approximately 190-194°C (decomposition). Optically active, specific rotation approximately +128° (in dioxane). Stable in air, discolors upon exposure to light.
Uses:Primarily used topically for the treatment of skin conditions including contact dermatitis, eczema, and neurodermatitis, providing significant anti-inflammatory, anti-allergic, and antipruritic effects. As an adrenocortical hormone drug with both glucocorticoid and mineralocorticoid activity, it is also used for replacement therapy in adrenocortical insufficiency and as adjunctive treatment for salt-losing congenital adrenal hyperplasia.
Technical Specifications:
Assay (C23H31FO6, on dried basis) is 97.0%-102.0%
Specific rotation is +125° to +132° (1% solution in dioxane, 20°C)
Loss on drying is not more than 1.0%
Heavy metals are not more than 20 ppm
Residue on ignition is not more than 0.1%
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常见问题
- 醋酸氟氢可的松的 CAS 号是多少？
- 醋酸氟氢可的松的 CAS 号是 514-36-3。
- 醋酸氟氢可的松的分子式和分子量是什么？
- 醋酸氟氢可的松的分子式为 C23H31FO6。
- 醋酸氟氢可的松的英文名称是什么？
- 醋酸氟氢可的松的英文名称为 Fludrocortisone Acetate。
- 醋酸氟氢可的松还有哪些别名？
- 醋酸氟氢可的松又称 9α-氟氢可的松、9α-氟皮质醇、氟可的索、9α-氟可的索、氟氢可的松、9α-氟皮质醇醋酸酯。
- 醋酸氟氢可的松有哪些供应商和生产厂家？
- 掌上化工当前收录 1 条醋酸氟氢可的松供应报价，来自 1 家供应商，可按地区、纯度、级别筛选对比。
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