5-chloro-2-fluoro-4-hydroxybenzoic acid (CAS No.593280-19-4)
- 中文别名
- 2-氟-5-氯-4-羟基苯甲酸；5-氯-2-氟-4-羟基安息香酸
- 英文名称
- 5-Chloro-2-fluoro-4-hydroxybenzoic acid
- 分子式
- C7H4ClFO3
- 分子量
- 190.56
- 所属类别
- 中间体
- 物化性质
- 类白色至浅黄色结晶性粉末；具有羧酸和酚羟基官能团，可溶于乙醇、二甲基亚砜、乙酸乙酯及稀碱溶液，微溶于水；密度约1.6 g/cm³，加热至约200°C以上可能分解。
- 外观
- 类白色至浅黄色结晶性粉末
- 熔点
- 约200°C以上分解
English description（英文原文，共 1149 字符）
Product Name:5-Chloro-2-fluoro-4-hydroxybenzoic acid
English Name:5-Chloro-2-fluoro-4-hydroxybenzoic acid
CAS No.:593280-19-4
Aliases:2-Fluoro-5-chloro-4-hydroxybenzoic acid, 5-Chloro-2-fluoro-4-hydroxybenzenecarboxylic acid
Molecular Formula:C7H4ClFO3
Physical Properties:Off-white to pale yellow crystalline powder. Contains carboxylic acid and phenolic hydroxyl functional groups; soluble in ethanol, dimethyl sulfoxide, ethyl acetate, and dilute alkali solutions, slightly soluble in water. Density about 1.6 g/cm³; may decompose above approximately 200 °C.
Uses:Serves as an intermediate in pharmaceutical and fine chemical synthesis, mainly for preparing active pharmaceutical molecules bearing fluorinated aromatic rings. It is also used in the development of kinase inhibitors, antibacterial/anti-inflammatory lead compounds, and agrochemicals, making it an important scaffold in small-molecule modification and drug discovery.
Technical Specifications:
Purity (HPLC): ≥98%
Appearance: off-white to pale yellow crystalline powder
Molecular weight: 190.56
Melting point: decomposes above approximately 200 °C
Loss on drying: ≤0.5%
English Name:5-Chloro-2-fluoro-4-hydroxybenzoic acid
CAS No.:593280-19-4
Aliases:2-Fluoro-5-chloro-4-hydroxybenzoic acid, 5-Chloro-2-fluoro-4-hydroxybenzenecarboxylic acid
Molecular Formula:C7H4ClFO3
Physical Properties:Off-white to pale yellow crystalline powder. Contains carboxylic acid and phenolic hydroxyl functional groups; soluble in ethanol, dimethyl sulfoxide, ethyl acetate, and dilute alkali solutions, slightly soluble in water. Density about 1.6 g/cm³; may decompose above approximately 200 °C.
Uses:Serves as an intermediate in pharmaceutical and fine chemical synthesis, mainly for preparing active pharmaceutical molecules bearing fluorinated aromatic rings. It is also used in the development of kinase inhibitors, antibacterial/anti-inflammatory lead compounds, and agrochemicals, making it an important scaffold in small-molecule modification and drug discovery.
Technical Specifications:
Purity (HPLC): ≥98%
Appearance: off-white to pale yellow crystalline powder
Molecular weight: 190.56
Melting point: decomposes above approximately 200 °C
Loss on drying: ≤0.5%
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常见问题
- 5-chloro-2-fluoro-4-hydroxybenzoic acid的 CAS 号是多少？
- 5-chloro-2-fluoro-4-hydroxybenzoic acid的 CAS 号是 593280-19-4。
- 5-chloro-2-fluoro-4-hydroxybenzoic acid的分子式和分子量是什么？
- 5-chloro-2-fluoro-4-hydroxybenzoic acid的分子式为 C7H4ClFO3，分子量约 190.56。
- 5-chloro-2-fluoro-4-hydroxybenzoic acid的英文名称是什么？
- 5-chloro-2-fluoro-4-hydroxybenzoic acid的英文名称为 5-Chloro-2-fluoro-4-hydroxybenzoic acid。
- 5-chloro-2-fluoro-4-hydroxybenzoic acid还有哪些别名？
- 5-chloro-2-fluoro-4-hydroxybenzoic acid又称 2-氟-5-氯-4-羟基苯甲酸、5-氯-2-氟-4-羟基安息香酸。
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