司美替尼 (CAS No.606143-52-6)
- 中文别名
- AZD6244；ARRY-142886
- 英文名称
- Selumetinib
- 分子式
- C17H15BrClFN4O3
- 分子量
- 457.69 English Version
- 所属类别
- 中间体
- 物化性质
- 白色至类白色固体粉末。可溶于DMSO、DMF，微溶于甲醇，几乎不溶于水。需避光、密封、-20℃低温保存。
- 纯度
- ≥98% (HPLC)
- 外观
- 白色至类白色固体粉末
- 溶解性
- 溶于DMSO、DMF，微溶于甲醇，几乎不溶于水
- 储存条件
- 避光、密封，-20℃保存
English description（英文原文，共 993 字符）
Product Name:Selumetinib
English Name:Selumetinib
CAS No.:606143-52-6
Aliases:AZD6244, ARRY-142886
Molecular Formula:C17H15BrClFN4O3
Physical Properties:White to off-white solid powder. Soluble in DMSO and DMF, slightly soluble in methanol, practically insoluble in water. Store sealed at -20°C, protected from light.
Uses:Selumetinib is a reversible inhibitor of MEK1/2 that suppresses tumor cell proliferation by blocking the RAS/RAF/MEK/ERK signaling pathway. It is used for the treatment of symptomatic, inoperable plexiform neurofibromas associated with neurofibromatosis type 1, and is being investigated in clinical studies for solid tumors including melanoma, non-small cell lung cancer, and thyroid cancer.
Technical Specifications:
Purity: ≥98% (HPLC)
Appearance: white to off-white solid powder
Solubility: soluble in DMSO and DMF, slightly soluble in methanol, practically insoluble in water
Storage: store sealed at -20°C, protected from light
Molecular weight: 457.69
English Name:Selumetinib
CAS No.:606143-52-6
Aliases:AZD6244, ARRY-142886
Molecular Formula:C17H15BrClFN4O3
Physical Properties:White to off-white solid powder. Soluble in DMSO and DMF, slightly soluble in methanol, practically insoluble in water. Store sealed at -20°C, protected from light.
Uses:Selumetinib is a reversible inhibitor of MEK1/2 that suppresses tumor cell proliferation by blocking the RAS/RAF/MEK/ERK signaling pathway. It is used for the treatment of symptomatic, inoperable plexiform neurofibromas associated with neurofibromatosis type 1, and is being investigated in clinical studies for solid tumors including melanoma, non-small cell lung cancer, and thyroid cancer.
Technical Specifications:
Purity: ≥98% (HPLC)
Appearance: white to off-white solid powder
Solubility: soluble in DMSO and DMF, slightly soluble in methanol, practically insoluble in water
Storage: store sealed at -20°C, protected from light
Molecular weight: 457.69
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常见问题
- 司美替尼的 CAS 号是多少？
- 司美替尼的 CAS 号是 606143-52-6。
- 司美替尼的分子式和分子量是什么？
- 司美替尼的分子式为 C17H15BrClFN4O3，分子量约 457.69 English Version。
- 司美替尼的英文名称是什么？
- 司美替尼的英文名称为 Selumetinib。
- 司美替尼还有哪些别名？
- 司美替尼又称 AZD6244、ARRY-142886。
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- 掌上化工当前收录 1 条司美替尼供应报价，来自 1 家供应商，可按地区、纯度、级别筛选对比。
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- 掌上化工司美替尼产品页汇总了各供应商的最新报价与规格，地址：/chemicals/606143-52-6/。部分供应商价格为电议，可通过页面上的询价功能直接获取。
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