LY2109761 (CAS No.700874-71-1)
- 中文别名
- TGF-β受体抑制剂LY2109761；4-[4-(2,3-二氢-1H-吡啶并[3,4-b]吲哚-4-基甲基)哌嗪-1-基]苯甲酸
- 英文名称
- LY2109761
- 分子式
- C26H27N5O2
- 所属类别
- 试剂实验设备
- 物化性质
- 白色至类白色固体粉末，溶于DMSO、DMF等有机溶剂，微溶于水。在-20°C下避光密封保存稳定。
- 纯度
- ≥98% (HPLC)
- 外观
- 白色至类白色固体粉末
- 溶解性
- DMSO ≥50 mg/mL，甲醇 ≥10 mg/mL，微溶于水
- 储存条件
- -20°C，避光密封保存
English description（英文原文，共 990 字符）
Product Name:LY2109761
English Name:LY2109761
CAS No.:700874-71-1
Aliases:TGF-β receptor inhibitor LY2109761, 4-[4-(2,3-dihydro-1H-pyrido[3,4-b]indol-4-ylmethyl)piperazin-1-yl]benzoic acid
Molecular Formula:C26H27N5O2
Physical Properties:White to off-white solid powder, soluble in DMSO, DMF and other organic solvents, slightly soluble in water. Stable when stored sealed at -20°C protected from light.
Uses:LY2109761 is a selective dual inhibitor of TGF-β receptor type I kinase (ALK5) and type II kinase, effectively blocking TGF-β signaling pathway. It is widely used in mechanistic studies and drug screening for tumor microenvironment, epithelial-mesenchymal transition (EMT), and fibrotic diseases.
Technical Specifications:
Purity: ≥98% (HPLC)
Appearance: white to off-white solid powder
Molecular formula: C26H27N5O2, molecular weight: 441.52
Solubility: DMSO ≥50 mg/mL, methanol ≥10 mg/mL, slightly soluble in water
Storage: store sealed at -20°C, protected from light
English Name:LY2109761
CAS No.:700874-71-1
Aliases:TGF-β receptor inhibitor LY2109761, 4-[4-(2,3-dihydro-1H-pyrido[3,4-b]indol-4-ylmethyl)piperazin-1-yl]benzoic acid
Molecular Formula:C26H27N5O2
Physical Properties:White to off-white solid powder, soluble in DMSO, DMF and other organic solvents, slightly soluble in water. Stable when stored sealed at -20°C protected from light.
Uses:LY2109761 is a selective dual inhibitor of TGF-β receptor type I kinase (ALK5) and type II kinase, effectively blocking TGF-β signaling pathway. It is widely used in mechanistic studies and drug screening for tumor microenvironment, epithelial-mesenchymal transition (EMT), and fibrotic diseases.
Technical Specifications:
Purity: ≥98% (HPLC)
Appearance: white to off-white solid powder
Molecular formula: C26H27N5O2, molecular weight: 441.52
Solubility: DMSO ≥50 mg/mL, methanol ≥10 mg/mL, slightly soluble in water
Storage: store sealed at -20°C, protected from light
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常见问题
- LY2109761的 CAS 号是多少？
- LY2109761的 CAS 号是 700874-71-1。
- LY2109761的分子式和分子量是什么？
- LY2109761的分子式为 C26H27N5O2。
- LY2109761的英文名称是什么？
- LY2109761的英文名称为 LY2109761。
- LY2109761还有哪些别名？
- LY2109761又称 TGF-β受体抑制剂LY2109761、4-[4-(2,3-二氢-1H-吡啶并[3,4-b]吲哚-4-基甲基)哌嗪-1-基]苯甲酸。
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