2-((4R,6R)-6-(2-(2-(4-氟苯基)-4-((4-(羟甲基)苯基)氨甲酰)-5-异丙基-3-苯基-1H- (CAS No.805241-63-8)
- 中文别名
- 阿托伐他汀中间体；(4R,6R)-6-(2-(2-(4-氟苯基)-4-((4-(羟甲基)苯基)氨基甲酰基)-5-异丙基-3-苯基-1H-吡咯-1-基)乙基)-2,2-二甲基-1,3-二氧六环-4-乙酸
- 英文名称
- 2-((4R,6R)-6-(2-(2-(4-fluorophenyl)-4-((4-(hydroxymethyl)phenyl)carbamoyl)-5-isopropyl-3-phenyl-1H-pyrrol-1-yl)ethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetic acid
- 分子式
- C37H41FN2O6
- 所属类别
- 中间体
- 物化性质
- 白色至类白色结晶粉末，熔点大于150°C（分解），密度约1.2 g/cm³。溶于二氯甲烷、乙醇、乙酸乙酯等有机溶剂，不溶于水。对光和热敏感，需在2-8°C下避光密封保存。
- 技术参数
- 含量（HPLC）≥98%
- 外观
- 白色至类白色粉末 干燥失重≤0.5% 单一杂质≤0.5% 灼烧残渣≤0.2%
English description（英文原文，共 1299 字符）
Product Name:2-((4R,6R)-6-(2-(2-(4-fluorophenyl)-4-((4-(hydroxymethyl)phenyl)carbamoyl)-5-isopropyl-3-phenyl-1H-pyrrol-1-yl)ethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetic acid
English Name:2-((4R,6R)-6-(2-(2-(4-fluorophenyl)-4-((4-(hydroxymethyl)phenyl)carbamoyl)-5-isopropyl-3-phenyl-1H-pyrrol-1-yl)ethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetic acid
CAS No.:805241-63-8
Aliases:Atorvastatin intermediate
Molecular Formula:C37H41FN2O6
Physical Properties:White to off-white crystalline powder. Melting point above 150°C (decomposition). Density approximately 1.2 g/cm³. Soluble in dichloromethane, ethanol, ethyl acetate and other organic solvents; insoluble in water. Sensitive to light and heat, store at 2-8°C in a sealed container protected from light.
Uses:This product is an important intermediate for the synthesis of statin lipid-lowering drugs, particularly for constructing pyrrole derivatives with a hydroxymethylphenylcarbamoyl side chain. It is used in the research and preparation of atorvastatin analogs and serves as a key raw material for studying the effects of fluorophenyl and isopropyl substitution in medicinal chemistry.
Technical Specifications:
Assay (HPLC) ≥98%
Appearance: white to off-white powder
Loss on drying ≤0.5%
Single impurity ≤0.5%
Residue on ignition ≤0.2%
English Name:2-((4R,6R)-6-(2-(2-(4-fluorophenyl)-4-((4-(hydroxymethyl)phenyl)carbamoyl)-5-isopropyl-3-phenyl-1H-pyrrol-1-yl)ethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetic acid
CAS No.:805241-63-8
Aliases:Atorvastatin intermediate
Molecular Formula:C37H41FN2O6
Physical Properties:White to off-white crystalline powder. Melting point above 150°C (decomposition). Density approximately 1.2 g/cm³. Soluble in dichloromethane, ethanol, ethyl acetate and other organic solvents; insoluble in water. Sensitive to light and heat, store at 2-8°C in a sealed container protected from light.
Uses:This product is an important intermediate for the synthesis of statin lipid-lowering drugs, particularly for constructing pyrrole derivatives with a hydroxymethylphenylcarbamoyl side chain. It is used in the research and preparation of atorvastatin analogs and serves as a key raw material for studying the effects of fluorophenyl and isopropyl substitution in medicinal chemistry.
Technical Specifications:
Assay (HPLC) ≥98%
Appearance: white to off-white powder
Loss on drying ≤0.5%
Single impurity ≤0.5%
Residue on ignition ≤0.2%
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常见问题
- 2-((4R,6R)-6-(2-(2-(4-氟苯基)-4-((4-(羟甲基)苯基)氨甲酰)-5-异丙基-3-苯基-1H-的 CAS 号是多少？
- 2-((4R,6R)-6-(2-(2-(4-氟苯基)-4-((4-(羟甲基)苯基)氨甲酰)-5-异丙基-3-苯基-1H-的 CAS 号是 805241-63-8。
- 2-((4R,6R)-6-(2-(2-(4-氟苯基)-4-((4-(羟甲基)苯基)氨甲酰)-5-异丙基-3-苯基-1H-的分子式和分子量是什么？
- 2-((4R,6R)-6-(2-(2-(4-氟苯基)-4-((4-(羟甲基)苯基)氨甲酰)-5-异丙基-3-苯基-1H-的分子式为 C37H41FN2O6。
- 2-((4R,6R)-6-(2-(2-(4-氟苯基)-4-((4-(羟甲基)苯基)氨甲酰)-5-异丙基-3-苯基-1H-的英文名称是什么？
- 2-((4R,6R)-6-(2-(2-(4-氟苯基)-4-((4-(羟甲基)苯基)氨甲酰)-5-异丙基-3-苯基-1H-的英文名称为 2-((4R,6R)-6-(2-(2-(4-fluorophenyl)-4-((4-(hydroxymethyl)phenyl)carbamoyl)-5-isopropyl-3-phenyl-1H-pyrrol-1-yl)ethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetic acid。
- 2-((4R,6R)-6-(2-(2-(4-氟苯基)-4-((4-(羟甲基)苯基)氨甲酰)-5-异丙基-3-苯基-1H-还有哪些别名？
- 2-((4R,6R)-6-(2-(2-(4-氟苯基)-4-((4-(羟甲基)苯基)氨甲酰)-5-异丙基-3-苯基-1H-又称 阿托伐他汀中间体、(4R,6R)-6-(2-(2-(4-氟苯基)-4-((4-(羟甲基)苯基)氨基甲酰基)-5-异丙基-3-苯基-1H-吡咯-1-基)乙基)-2,2-二甲基-1,3-二氧六环-4-乙酸。
- 2-((4R,6R)-6-(2-(2-(4-氟苯基)-4-((4-(羟甲基)苯基)氨甲酰)-5-异丙基-3-苯基-1H-有哪些供应商和生产厂家？
- 掌上化工当前收录 1 条2-((4R,6R)-6-(2-(2-(4-氟苯基)-4-((4-(羟甲基)苯基)氨甲酰)-5-异丙基-3-苯基-1H-供应报价，来自 1 家供应商，可按地区、纯度、级别筛选对比。
- 2-((4R,6R)-6-(2-(2-(4-氟苯基)-4-((4-(羟甲基)苯基)氨甲酰)-5-异丙基-3-苯基-1H-的供应商主要分布在哪些地区？
- 2-((4R,6R)-6-(2-(2-(4-氟苯基)-4-((4-(羟甲基)苯基)氨甲酰)-5-异丙基-3-苯基-1H-的供应商主要分布在 上海市（1 条） 等地。
- 2-((4R,6R)-6-(2-(2-(4-氟苯基)-4-((4-(羟甲基)苯基)氨甲酰)-5-异丙基-3-苯基-1H-有哪些级别可选？
- 平台上2-((4R,6R)-6-(2-(2-(4-氟苯基)-4-((4-(羟甲基)苯基)氨甲酰)-5-异丙基-3-苯基-1H-的供应级别包括 工业级。
- 2-((4R,6R)-6-(2-(2-(4-氟苯基)-4-((4-(羟甲基)苯基)氨甲酰)-5-异丙基-3-苯基-1H-的报价单位是什么？
- 2-((4R,6R)-6-(2-(2-(4-氟苯基)-4-((4-(羟甲基)苯基)氨甲酰)-5-异丙基-3-苯基-1H-的报价单位主要有 千克。
- 哪里可以查到2-((4R,6R)-6-(2-(2-(4-氟苯基)-4-((4-(羟甲基)苯基)氨甲酰)-5-异丙基-3-苯基-1H-的价格？
- 掌上化工2-((4R,6R)-6-(2-(2-(4-氟苯基)-4-((4-(羟甲基)苯基)氨甲酰)-5-异丙基-3-苯基-1H-产品页汇总了各供应商的最新报价与规格，地址：/chemicals/805241-63-8/。部分供应商价格为电议，可通过页面上的询价功能直接获取。
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