2氯三苯甲基树脂 (CAS No.934816-82-7)
- 物化性质
- 以1% DVB交联的聚苯乙烯树脂，功能基团为2-氯三苯甲基氯。载量0.3~0.8 mmol/g，粒径100~200目，在二氯甲烷、N,N-二甲基甲酰胺等溶剂中具有高溶胀性。树脂间隔臂较常规产品更长，有利于大位阻保护性氨基酸接近偶联位点。
- 纯度
- ≥99.0% 在DCM、DMF中溶胀性高
English description（英文原文，共 1146 字符）
Product Name:2-Chlorotrityl Chloride Resin
English Name:2-Chlorotrityl Chloride Resin
CAS No.:934816-82-7
Aliases:2-CTA Resin, 2-Chlorotrityl Alcohol Resin
Physical Properties:Polystyrene resin crosslinked with 1% DVB, functionalized with 2-chlorotrityl chloride groups. Loading capacity: 0.3-0.8 mmol/g; particle size: 100-200 mesh. Exhibits high swelling in dichloromethane and N,N-dimethylformamide. The resin spacer arm is longer than that of conventional products, facilitating access of bulky protected amino acids to the coupling sites.
Uses:Used as a solid support in solid-phase peptide synthesis, particularly for the preparation of peptide segments with a C-terminal free carboxylic acid. The 2-chlorotrityl functionality enables cleavage under mild acidic conditions while retaining side-chain protecting groups. The extended spacer arm improves the coupling efficiency of sterically hindered amino acids (e.g., Arg, Trp, Gln), resulting in high peptide purity and yield.
Technical Specifications:
Loading capacity: 0.3-0.8 mmol/g
Particle size: 100-200 mesh
Crosslinking: 1% DVB
Purity: ≥99.0%
High swelling in DCM and DMF
English Name:2-Chlorotrityl Chloride Resin
CAS No.:934816-82-7
Aliases:2-CTA Resin, 2-Chlorotrityl Alcohol Resin
Physical Properties:Polystyrene resin crosslinked with 1% DVB, functionalized with 2-chlorotrityl chloride groups. Loading capacity: 0.3-0.8 mmol/g; particle size: 100-200 mesh. Exhibits high swelling in dichloromethane and N,N-dimethylformamide. The resin spacer arm is longer than that of conventional products, facilitating access of bulky protected amino acids to the coupling sites.
Uses:Used as a solid support in solid-phase peptide synthesis, particularly for the preparation of peptide segments with a C-terminal free carboxylic acid. The 2-chlorotrityl functionality enables cleavage under mild acidic conditions while retaining side-chain protecting groups. The extended spacer arm improves the coupling efficiency of sterically hindered amino acids (e.g., Arg, Trp, Gln), resulting in high peptide purity and yield.
Technical Specifications:
Loading capacity: 0.3-0.8 mmol/g
Particle size: 100-200 mesh
Crosslinking: 1% DVB
Purity: ≥99.0%
High swelling in DCM and DMF
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常见问题
- 2氯三苯甲基树脂的 CAS 号是多少？
- 2氯三苯甲基树脂的 CAS 号是 934816-82-7。
- 2氯三苯甲基树脂的英文名称是什么？
- 2氯三苯甲基树脂的英文名称为 2-Chlorotrityl Chloride Resin。
- 2氯三苯甲基树脂还有哪些别名？
- 2氯三苯甲基树脂又称 2-CTA Resin、2-氯三苯甲醇树脂。
- 2氯三苯甲基树脂有哪些供应商和生产厂家？
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