阿托伐他汀杂质F (CAS No.1105067-87-5)
- 中文别名
- Atorvastatin N-(3,5-Dihydroxy-7-heptanoic Acid)amide；(3R,5R)-7-[[(3R,5R)-7-[2-(4-Fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]-3,5-dihydroxy-1-oxoheptyl]amino]-3,5-dihydroxy-heptanoic Acid Calcium Salt
- 英文名称
- Atorvastatin Impurity F
- 分子式
- C80H94CaF2N6O16
- 所属类别
- 试剂实验设备
- 物化性质
- 白色至类白色固体。分子量约为1473.71，精确质量为1472.63，PSA为382.32，LogP约为11.63。溶于DMSO、DMF等有机溶剂，微溶于水。该杂质为阿托伐他汀的钙盐形式相关物质，具有较高的亲脂性，应在避光、低温、密封条件下保存。
- 纯度
- ≥98%
- 外观
- 白色至类白色固体
- 储存条件
- -20℃避光、密封保存
English description（英文原文，共 1397 字符）
Product Name:Atorvastatin Impurity F
English Name:Atorvastatin Impurity F
CAS No.:1105067-87-5
Aliases:Atorvastatin N-(3,5-Dihydroxy-7-heptanoic Acid)amide, (3R,5R)-7-[[(3R,5R)-7-[2-(4-Fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]-3,5-dihydroxy-1-oxoheptyl]amino]-3,5-dihydroxy-heptanoic Acid Calcium Salt
Molecular Formula:C80H94CaF2N6O16
Physical Properties:White to off-white solid. Molecular weight is approximately 1473.71, exact mass is 1472.63, PSA is 382.32, and LogP is about 11.63. Soluble in organic solvents such as DMSO and DMF, slightly soluble in water. This impurity is a calcium salt-related substance of atorvastatin with high lipophilicity and should be stored sealed, protected from light, and kept at low temperature.
Uses:Atorvastatin Impurity F is mainly used as a reference standard for studying the synthesis and degradation pathways of atorvastatin. It is suitable for new drug research and development, quality control, and laboratory research. It can be used as a standard substance in HPLC analysis, drug impurity profiling, and method validation for qualitative and quantitative impurity analysis.
Technical Specifications:
Purity: ≥98%
Packaging: 25MG/50MG/100MG/200MG
Appearance: white to off-white solid
Storage: store sealed at -20°C, protected from light
Usage: laboratory research and impurity reference analysis
English Name:Atorvastatin Impurity F
CAS No.:1105067-87-5
Aliases:Atorvastatin N-(3,5-Dihydroxy-7-heptanoic Acid)amide, (3R,5R)-7-[[(3R,5R)-7-[2-(4-Fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]-3,5-dihydroxy-1-oxoheptyl]amino]-3,5-dihydroxy-heptanoic Acid Calcium Salt
Molecular Formula:C80H94CaF2N6O16
Physical Properties:White to off-white solid. Molecular weight is approximately 1473.71, exact mass is 1472.63, PSA is 382.32, and LogP is about 11.63. Soluble in organic solvents such as DMSO and DMF, slightly soluble in water. This impurity is a calcium salt-related substance of atorvastatin with high lipophilicity and should be stored sealed, protected from light, and kept at low temperature.
Uses:Atorvastatin Impurity F is mainly used as a reference standard for studying the synthesis and degradation pathways of atorvastatin. It is suitable for new drug research and development, quality control, and laboratory research. It can be used as a standard substance in HPLC analysis, drug impurity profiling, and method validation for qualitative and quantitative impurity analysis.
Technical Specifications:
Purity: ≥98%
Packaging: 25MG/50MG/100MG/200MG
Appearance: white to off-white solid
Storage: store sealed at -20°C, protected from light
Usage: laboratory research and impurity reference analysis
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常见问题
- 阿托伐他汀杂质F的 CAS 号是多少？
- 阿托伐他汀杂质F的 CAS 号是 1105067-87-5。
- 阿托伐他汀杂质F的分子式和分子量是什么？
- 阿托伐他汀杂质F的分子式为 C80H94CaF2N6O16。
- 阿托伐他汀杂质F的英文名称是什么？
- 阿托伐他汀杂质F的英文名称为 Atorvastatin Impurity F。
- 阿托伐他汀杂质F还有哪些别名？
- 阿托伐他汀杂质F又称 Atorvastatin N-(3,5-Dihydroxy-7-heptanoic Acid)amide、(3R,5R)-7-[[(3R,5R)-7-[2-(4-Fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]-3,5-dihydroxy-1-oxoheptyl]amino]-3,5-dihydroxy-heptanoic Acid Calcium Salt。
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