5-溴-1H-吡咯并[2,3-C]吡啶-2(3H)-酮 (CAS No.1217002-90-8)

Product Name:5-Bromo-1H-pyrrolo[2,3-c]pyridin-2(3H)-one

English Name:5-Bromo-1H-pyrrolo[2,3-c]pyridin-2(3H)-one

CAS No.:1217002-90-8

Aliases:5-Bromo-2-oxo-2,3-dihydro-1H-pyrrolo[2,3-c]pyridine, 5-Bromo-1,3-dihydro-2H-pyrrolo[2,3-c]pyridin-2-one, 5-Bromo-1H-pyrrolo[2,3-c]pyridin-2-one

Molecular Formula:C7H5BrN2O

Physical Properties:White to off-white crystalline powder. Slightly soluble in water; soluble in organic solvents such as N,N-dimethylformamide (DMF), dimethyl sulfoxide (DMSO), and methanol. It is a pyrrolopyridinone heterocyclic compound, stable at room temperature and prone to decomposition when heated above its melting point. Molecular weight: 213.03.

Uses:This compound is an important pharmaceutical and chemical intermediate, widely used in the synthesis of tyrosine kinase inhibitors, antitumor agents, and other bioactive molecules. Its pyrrolopyridinone fused-ring skeleton can serve as a core structural building block for structural modification and lead optimization in drug discovery. It is also used in organic synthesis for derivatization reactions such as coupling and amination.

Technical Specifications:

Appearance: white to off-white crystalline powder

Molecular formula: C7H5BrN2O

Molecular weight: 213.03

Purity: ≥97% (HPLC)

Storage: keep sealed, protected from light, in a cool, dry place