(R)-2-氨基-3-(7-甲基-1H-吲唑-5-基)丙酸甲酯二盐酸盐 (CAS No.1414976-14-9)

Product Name:methyl (2R)-2-amino-3-(7-methyl-1H-indazol-5-yl)propanoate dihydrochloride

English Name:methyl (2R)-2-amino-3-(7-methyl-1H-indazol-5-yl)propanoate dihydrochloride

CAS No.:1414976-14-9

Aliases:7-methylindazole alanine methyl ester dihydrochloride, (2R)-2-amino-3-(7-methyl-1H-indazol-5-yl)propanoic acid methyl ester dihydrochloride, D-7-methylindazole alanine methyl ester dihydrochloride

Molecular Formula:C12H16ClN3O2

Physical Properties:White to off-white solid powder, soluble in water and alcohols such as methanol and ethanol, slightly soluble in ethyl acetate and diethyl ether. Melting point range approximately 180-185°C (decomposes). Hygroscopic, should be stored under dry conditions and avoid prolonged exposure to air.

Uses:This product is a chiral amino acid derivative containing an indazole ring, mainly used as a pharmaceutical intermediate for the synthesis of bioactive drug candidates such as kinase inhibitors and receptor modulators. In drug discovery, it is particularly suitable for constructing active compounds bearing the 7-methylindazole scaffold, applied in the structural optimization and screening of antitumor and anti-inflammatory agents.

Technical Specifications:

Appearance: white to off-white solid powder

Assay (HPLC): ≥98.0%

Optical purity (ee): ≥98.0%

Loss on drying: ≤0.5%

Storage: stored in a cool dry place at 2-8°C, protected from light and moisture