N-((S)-1-(3-(3-氨基-4-氯-1-(2,2,2-三氟乙基)-1H-吲唑-7-基)-6-(3-甲基-3-(甲 (CAS No.2375020-20-3)
- 中文别名
- 化合物 2375020-20-3；三氟乙基吲唑类BTK抑制剂中间体
- 英文名称
- N-[(1S)-1-[3-[3-amino-4-chloro-1-(2,2,2-trifluoroethyl)-1H-indazol-7-yl]-6-[3-methyl-3-(methylamino)pyrrolidin-1-yl]pyridin-2-yl]-2-hydroxyethyl]-3-chloro-4-(methylamino)benzamide
- 分子式
- C30H33Cl2F3N8O2
- 分子量
- 665.54 g/mol
- InChIKey
- ISVGOULQBYJQFS-GSLIJJQTSA-N
- 所属类别
- 中间体
- 物化性质
- 白色至类白色固体粉末，熔点为220-225°C（分解），易溶于二甲基亚砜(DMSO)、N,N-二甲基甲酰胺(DMF)，微溶于甲醇，几乎不溶于水。在-20°C避光条件下稳定。
- 外观
- 白色至类白色固体粉末
- 储存条件
- -20°C，避光，密封保存
English description（英文原文，共 1315 字符）
Product Name:N-[(1S)-1-[3-[3-amino-4-chloro-1-(2,2,2-trifluoroethyl)-1H-indazol-7-yl]-6-[3-methyl-3-(methylamino)pyrrolidin-1-yl]pyridin-2-yl]-2-hydroxyethyl]-3-chloro-4-(methylamino)benzamide
English Name:N-[(1S)-1-[3-[3-amino-4-chloro-1-(2,2,2-trifluoroethyl)-1H-indazol-7-yl]-6-[3-methyl-3-(methylamino)pyrrolidin-1-yl]pyridin-2-yl]-2-hydroxyethyl]-3-chloro-4-(methylamino)benzamide
CAS No.:2375020-20-3
Aliases:Compound 2375020-20-3, Trifluoroethyl indazole BTK inhibitor intermediate
Molecular Formula:C30H33Cl2F3N8O2
Physical Properties:White to off-white solid powder, melting point 220-225°C (decomp.), freely soluble in dimethyl sulfoxide (DMSO) and N,N-dimethylformamide (DMF), slightly soluble in methanol, practically insoluble in water. Stable at -20°C protected from light.
Uses:This product is a pharmaceutical intermediate mainly used for the synthesis of Bruton's tyrosine kinase (BTK) inhibitor-type targeted antitumor drugs. As a key scaffold fragment, it introduces indazole and pyrrolidine moieties for constructing candidate drug molecules with selective inhibitory activity.
Technical Specifications:
Purity (HPLC): ≥98.0%
Appearance: white to off-white solid powder
Molecular weight: 665.54 g/mol
Water content: ≤0.5% (K.F.)
Storage condition: -20°C, protected from light, sealed
English Name:N-[(1S)-1-[3-[3-amino-4-chloro-1-(2,2,2-trifluoroethyl)-1H-indazol-7-yl]-6-[3-methyl-3-(methylamino)pyrrolidin-1-yl]pyridin-2-yl]-2-hydroxyethyl]-3-chloro-4-(methylamino)benzamide
CAS No.:2375020-20-3
Aliases:Compound 2375020-20-3, Trifluoroethyl indazole BTK inhibitor intermediate
Molecular Formula:C30H33Cl2F3N8O2
Physical Properties:White to off-white solid powder, melting point 220-225°C (decomp.), freely soluble in dimethyl sulfoxide (DMSO) and N,N-dimethylformamide (DMF), slightly soluble in methanol, practically insoluble in water. Stable at -20°C protected from light.
Uses:This product is a pharmaceutical intermediate mainly used for the synthesis of Bruton's tyrosine kinase (BTK) inhibitor-type targeted antitumor drugs. As a key scaffold fragment, it introduces indazole and pyrrolidine moieties for constructing candidate drug molecules with selective inhibitory activity.
Technical Specifications:
Purity (HPLC): ≥98.0%
Appearance: white to off-white solid powder
Molecular weight: 665.54 g/mol
Water content: ≤0.5% (K.F.)
Storage condition: -20°C, protected from light, sealed
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常见问题
- N-((S)-1-(3-(3-氨基-4-氯-1-(2,2,2-三氟乙基)-1H-吲唑-7-基)-6-(3-甲基-3-(甲的 CAS 号是多少？
- N-((S)-1-(3-(3-氨基-4-氯-1-(2,2,2-三氟乙基)-1H-吲唑-7-基)-6-(3-甲基-3-(甲的 CAS 号是 2375020-20-3。
- N-((S)-1-(3-(3-氨基-4-氯-1-(2,2,2-三氟乙基)-1H-吲唑-7-基)-6-(3-甲基-3-(甲的分子式和分子量是什么？
- N-((S)-1-(3-(3-氨基-4-氯-1-(2,2,2-三氟乙基)-1H-吲唑-7-基)-6-(3-甲基-3-(甲的分子式为 C30H33Cl2F3N8O2，分子量约 665.54 g/mol。
- N-((S)-1-(3-(3-氨基-4-氯-1-(2,2,2-三氟乙基)-1H-吲唑-7-基)-6-(3-甲基-3-(甲的英文名称是什么？
- N-((S)-1-(3-(3-氨基-4-氯-1-(2,2,2-三氟乙基)-1H-吲唑-7-基)-6-(3-甲基-3-(甲的英文名称为 N-[(1S)-1-[3-[3-amino-4-chloro-1-(2,2,2-trifluoroethyl)-1H-indazol-7-yl]-6-[3-methyl-3-(methylamino)pyrrolidin-1-yl]pyridin-2-yl]-2-hydroxyethyl]-3-chloro-4-(methylamino)benzamide。
- N-((S)-1-(3-(3-氨基-4-氯-1-(2,2,2-三氟乙基)-1H-吲唑-7-基)-6-(3-甲基-3-(甲还有哪些别名？
- N-((S)-1-(3-(3-氨基-4-氯-1-(2,2,2-三氟乙基)-1H-吲唑-7-基)-6-(3-甲基-3-(甲又称 化合物 2375020-20-3、三氟乙基吲唑类BTK抑制剂中间体。
- N-((S)-1-(3-(3-氨基-4-氯-1-(2,2,2-三氟乙基)-1H-吲唑-7-基)-6-(3-甲基-3-(甲有哪些供应商和生产厂家？
- 掌上化工当前收录 1 条N-((S)-1-(3-(3-氨基-4-氯-1-(2,2,2-三氟乙基)-1H-吲唑-7-基)-6-(3-甲基-3-(甲供应报价，来自 1 家供应商，可按地区、纯度、级别筛选对比。
- N-((S)-1-(3-(3-氨基-4-氯-1-(2,2,2-三氟乙基)-1H-吲唑-7-基)-6-(3-甲基-3-(甲的供应商主要分布在哪些地区？
- N-((S)-1-(3-(3-氨基-4-氯-1-(2,2,2-三氟乙基)-1H-吲唑-7-基)-6-(3-甲基-3-(甲的供应商主要分布在 上海市（1 条） 等地。
- N-((S)-1-(3-(3-氨基-4-氯-1-(2,2,2-三氟乙基)-1H-吲唑-7-基)-6-(3-甲基-3-(甲有哪些级别可选？
- 平台上N-((S)-1-(3-(3-氨基-4-氯-1-(2,2,2-三氟乙基)-1H-吲唑-7-基)-6-(3-甲基-3-(甲的供应级别包括 工业级。
- N-((S)-1-(3-(3-氨基-4-氯-1-(2,2,2-三氟乙基)-1H-吲唑-7-基)-6-(3-甲基-3-(甲的报价单位是什么？
- N-((S)-1-(3-(3-氨基-4-氯-1-(2,2,2-三氟乙基)-1H-吲唑-7-基)-6-(3-甲基-3-(甲的报价单位主要有 千克。
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- 掌上化工N-((S)-1-(3-(3-氨基-4-氯-1-(2,2,2-三氟乙基)-1H-吲唑-7-基)-6-(3-甲基-3-(甲产品页汇总了各供应商的最新报价与规格，地址：/chemicals/2375020-20-3/。部分供应商价格为电议，可通过页面上的询价功能直接获取。
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