4-[(4-甲基苯基)硫基]噻吩并[2,3-C]吡啶-2-甲酰胺 (CAS No.251992-66-2)
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- 物化性质
- 白色至类白色结晶性粉末；微溶于水，易溶于DMSO、DMF等有机溶剂。熔点约196~198℃。本品在常规储存条件下性质稳定，建议低温避光密封保存。
- 纯度
- ≥98%（HPLC法）
- 熔点
- 约196~198℃
- 溶解性
- DMSO中溶解度≥50 mg/mL，水中微溶
- 储存条件
- -20℃避光、密封保存
English description（英文原文，共 1064 字符）
Product Name:A 205804
English Name:A 205804
CAS No.:251992-66-2
Aliases:A-205804, 4-[(4-Methylphenyl)thio]thieno[2,3-c]pyridine-2-carboxamide, 4-(p-Tolylthio)thieno[2,3-c]pyridine-2-carboxamide
Molecular Formula:C15H12N2OS2
Physical Properties:White to off-white crystalline powder; sparingly soluble in water, freely soluble in DMSO, DMF and other organic solvents. Melting point approximately 196–198 °C. Stable under normal storage conditions; store sealed at low temperature, protected from light.
Uses:A 205804 is a potent inhibitor of ICAM-1 expression that suppresses TNF-α-induced upregulation of ICAM-1 and E-selectin, thereby blocking leukocyte adhesion to vascular endothelium. It is widely used as a tool molecule in research on inflammation, autoimmune diseases, and tumor metastasis.
Technical Specifications:
Purity: ≥98% (HPLC)
Molecular formula: C15H12N2OS2; Molecular weight: 300.40
Melting point: approximately 196–198 °C
Solubility: ≥50 mg/mL in DMSO; sparingly soluble in water
Storage: store sealed at -20 °C, protected from light
English Name:A 205804
CAS No.:251992-66-2
Aliases:A-205804, 4-[(4-Methylphenyl)thio]thieno[2,3-c]pyridine-2-carboxamide, 4-(p-Tolylthio)thieno[2,3-c]pyridine-2-carboxamide
Molecular Formula:C15H12N2OS2
Physical Properties:White to off-white crystalline powder; sparingly soluble in water, freely soluble in DMSO, DMF and other organic solvents. Melting point approximately 196–198 °C. Stable under normal storage conditions; store sealed at low temperature, protected from light.
Uses:A 205804 is a potent inhibitor of ICAM-1 expression that suppresses TNF-α-induced upregulation of ICAM-1 and E-selectin, thereby blocking leukocyte adhesion to vascular endothelium. It is widely used as a tool molecule in research on inflammation, autoimmune diseases, and tumor metastasis.
Technical Specifications:
Purity: ≥98% (HPLC)
Molecular formula: C15H12N2OS2; Molecular weight: 300.40
Melting point: approximately 196–198 °C
Solubility: ≥50 mg/mL in DMSO; sparingly soluble in water
Storage: store sealed at -20 °C, protected from light
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常见问题
- 4-[(4-甲基苯基)硫基]噻吩并[2,3-C]吡啶-2-甲酰胺的 CAS 号是多少？
- 4-[(4-甲基苯基)硫基]噻吩并[2,3-C]吡啶-2-甲酰胺的 CAS 号是 251992-66-2。
- 4-[(4-甲基苯基)硫基]噻吩并[2,3-C]吡啶-2-甲酰胺的分子式和分子量是什么？
- 4-[(4-甲基苯基)硫基]噻吩并[2,3-C]吡啶-2-甲酰胺的分子式为 C15H12N2OS2。
- 4-[(4-甲基苯基)硫基]噻吩并[2,3-C]吡啶-2-甲酰胺的英文名称是什么？
- 4-[(4-甲基苯基)硫基]噻吩并[2,3-C]吡啶-2-甲酰胺的英文名称为 A 205804。
- 4-[(4-甲基苯基)硫基]噻吩并[2,3-C]吡啶-2-甲酰胺还有哪些别名？
- 4-[(4-甲基苯基)硫基]噻吩并[2,3-C]吡啶-2-甲酰胺又称 A 205804、4-(对甲苯基硫基)噻吩并[2,3-c]吡啶-2-甲酰胺。
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