2'-F-2'-ARA-BZ-DA 亚磷酰胺单体 (CAS No.329187-86-2)
- 物化性质
- 白色至类白色固体粉末,可溶于乙腈、二氯甲烷等有机溶剂,微溶于甲醇和乙醇。对水和空气敏感,应在干燥惰性气体保护下储存。分子量875.94,高沸点化合物,遇热分解。
- 外观
- 白色至类白色固体粉末
- 溶解性
- 易溶于乙腈、二氯甲烷,微溶于甲醇、乙醇
- 储存条件
- 2-8°C,干燥避光,惰性气体保护,防潮
English description(英文原文,共 1451 字符)
Product Name:2'-Fluoro-2'-deoxy-ara-A-3'-phosphoramidite
English Name:2'-Fluoro-2'-deoxy-ara-A-3'-phosphoramidite
CAS No.:329187-86-2
Aliases:N6-Benzoyl-2'-fluoro-2'-deoxy-arabinofuranosyladenine 3'-phosphoramidite, 2'-Fluoro-2'-deoxy-D-arabinoadenosine phosphoramidite monomer
Molecular Formula:C47H51FN7O7P
Physical Properties:White to off-white solid powder, soluble in acetonitrile and dichloromethane, slightly soluble in methanol and ethanol. Sensitive to moisture and air; should be stored under dry inert gas protection. Molecular weight 875.94, high boiling point compound, decomposes upon heating.
Uses:This product is a 2'-fluoro-modified arabinonucleoside phosphoramidite monomer, primarily used in solid-phase oligonucleotide synthesis to introduce 2'-fluoro-2'-deoxyarabinonucleotide units into DNA/RNA analogs. Such modifications significantly enhance the nuclease stability and binding affinity of oligonucleotides to complementary strands, and are widely applied in the development and production of antisense oligonucleotide drugs, small interfering RNA, and nucleic acid aptamers.
Technical Specifications:
Molecular formula: C47H51FN7O7P, molecular weight: 875.94
Appearance: white to off-white solid powder
Purity (HPLC): ≥98%
Solubility: freely soluble in acetonitrile and dichloromethane, slightly soluble in methanol and ethanol
Storage: store at 2-8°C, dry and protected from light, under inert gas, moisture-proof
English Name:2'-Fluoro-2'-deoxy-ara-A-3'-phosphoramidite
CAS No.:329187-86-2
Aliases:N6-Benzoyl-2'-fluoro-2'-deoxy-arabinofuranosyladenine 3'-phosphoramidite, 2'-Fluoro-2'-deoxy-D-arabinoadenosine phosphoramidite monomer
Molecular Formula:C47H51FN7O7P
Physical Properties:White to off-white solid powder, soluble in acetonitrile and dichloromethane, slightly soluble in methanol and ethanol. Sensitive to moisture and air; should be stored under dry inert gas protection. Molecular weight 875.94, high boiling point compound, decomposes upon heating.
Uses:This product is a 2'-fluoro-modified arabinonucleoside phosphoramidite monomer, primarily used in solid-phase oligonucleotide synthesis to introduce 2'-fluoro-2'-deoxyarabinonucleotide units into DNA/RNA analogs. Such modifications significantly enhance the nuclease stability and binding affinity of oligonucleotides to complementary strands, and are widely applied in the development and production of antisense oligonucleotide drugs, small interfering RNA, and nucleic acid aptamers.
Technical Specifications:
Molecular formula: C47H51FN7O7P, molecular weight: 875.94
Appearance: white to off-white solid powder
Purity (HPLC): ≥98%
Solubility: freely soluble in acetonitrile and dichloromethane, slightly soluble in methanol and ethanol
Storage: store at 2-8°C, dry and protected from light, under inert gas, moisture-proof
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常见问题
- 2'-F-2'-ARA-BZ-DA 亚磷酰胺单体的 CAS 号是多少?
- 2'-F-2'-ARA-BZ-DA 亚磷酰胺单体的 CAS 号是 329187-86-2。
- 2'-F-2'-ARA-BZ-DA 亚磷酰胺单体的分子式和分子量是什么?
- 2'-F-2'-ARA-BZ-DA 亚磷酰胺单体的分子式为 C47H51FN7O7P。
- 2'-F-2'-ARA-BZ-DA 亚磷酰胺单体的英文名称是什么?
- 2'-F-2'-ARA-BZ-DA 亚磷酰胺单体的英文名称为 2'-Fluoro-2'-deoxy-ara-A-3'-phosphoramidite。
- 2'-F-2'-ARA-BZ-DA 亚磷酰胺单体还有哪些别名?
- 2'-F-2'-ARA-BZ-DA 亚磷酰胺单体又称 2'-氟-2'-脱氧阿拉伯糖腺苷亚磷酰胺单体、N6-苯甲酰基-2'-氟-2'-脱氧阿拉伯糖腺苷-3'-亚磷酰胺。
- 2'-F-2'-ARA-BZ-DA 亚磷酰胺单体有哪些供应商和生产厂家?
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