2-[1-[(2-氟苯基基)甲基]-1H-吡唑并[3 (CAS No.428854-24-4)

Product Name:2-[1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]pyrimidin-5-amine

English Name:2-[1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]pyrimidin-5-amine

CAS No.:428854-24-4

Aliases:2-[1-[(2-Fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]pyrimidin-5-amine, 1-(2-Fluorobenzyl)-3-(5-aminopyrimidin-2-yl)-1H-pyrazolo[3,4-b]pyridine

Molecular Formula:C17H13FN6

Physical Properties:White to off-white crystalline powder; melting point approximately 230–233 °C; freely soluble in DMSO and DMF, sparingly soluble in methanol and ethanol, practically insoluble in water.

Uses:As a heterocyclic aromatic amine bearing a pyrazolo[3,4-b]pyridine skeleton, this compound is mainly used as a pharmaceutical intermediate for the synthesis of JAK kinase inhibitor-active molecules, and is of value in the R&D of drugs for anti-inflammatory, anti-tumor and autoimmune disease therapies. It can also serve as an organic synthesis building block for constructing novel fluorine-containing heteroaromatic functional molecules.

Technical Specifications:

Purity (HPLC): ≥95%

Appearance: white to off-white crystalline powder

Molecular weight: 320.33

Storage conditions: store at 2–8 °C, protected from light, sealed and dry

Solubility: soluble in DMSO and DMF, sparingly soluble in methanol, practically insoluble in water