1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid, Mono(4-nitrophenyl) ester (CAS No.474424-15-2)
- 物化性质
- 白色至类白色固体,溶于DMSO、DMF等有机溶剂,微溶于水。作为活泼酯衍生物,可在温和条件下与伯胺发生酰化反应,形成稳定的酰胺键。
- 外观
- 白色至类白色固体
- 含量
- ≥95% (HPLC)
- 溶解性
- 溶于DMSO、DMF,微溶于水
- 储存条件
- 2-8℃避光密封保存
English description(英文原文,共 1085 字符)
Product Name:DOTA-mono(4-nitrophenyl) ester
English Name:DOTA-mono(4-nitrophenyl) ester
CAS No.:474424-15-2
Aliases:DOTA mono-p-nitrophenyl ester, 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid mono(4-nitrophenyl) ester
Molecular Formula:C22H31N5O10
Physical Properties:White to off-white solid, soluble in DMSO, DMF and other organic solvents, slightly soluble in water. As an active ester derivative, it reacts with primary amines under mild conditions to form stable amide bonds.
Uses:Used as a bifunctional chelating agent to conjugate with amino groups on peptides, antibodies or small-molecule ligands via the active ester moiety, introducing a DOTA chelating arm. The resulting conjugates are utilized for radiolabeling with isotopes such as Gallium-68 and Lutetium-177, widely applied in PET imaging and targeted radionuclide therapy.
Technical Specifications:
Molecular weight: 525.51
Appearance: white to off-white solid
Purity: ≥95% (HPLC)
Solubility: soluble in DMSO and DMF, slightly soluble in water
Storage: sealed and protected from light at 2-8°C
English Name:DOTA-mono(4-nitrophenyl) ester
CAS No.:474424-15-2
Aliases:DOTA mono-p-nitrophenyl ester, 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid mono(4-nitrophenyl) ester
Molecular Formula:C22H31N5O10
Physical Properties:White to off-white solid, soluble in DMSO, DMF and other organic solvents, slightly soluble in water. As an active ester derivative, it reacts with primary amines under mild conditions to form stable amide bonds.
Uses:Used as a bifunctional chelating agent to conjugate with amino groups on peptides, antibodies or small-molecule ligands via the active ester moiety, introducing a DOTA chelating arm. The resulting conjugates are utilized for radiolabeling with isotopes such as Gallium-68 and Lutetium-177, widely applied in PET imaging and targeted radionuclide therapy.
Technical Specifications:
Molecular weight: 525.51
Appearance: white to off-white solid
Purity: ≥95% (HPLC)
Solubility: soluble in DMSO and DMF, slightly soluble in water
Storage: sealed and protected from light at 2-8°C
共 1 家生产厂家、批发商,
1 条供应报价
供应报价
常见问题
- 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid, Mono(4-nitrophenyl) ester的 CAS 号是多少?
- 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid, Mono(4-nitrophenyl) ester的 CAS 号是 474424-15-2。
- 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid, Mono(4-nitrophenyl) ester的分子式和分子量是什么?
- 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid, Mono(4-nitrophenyl) ester的分子式为 C22H31N5O10,分子量约 525.51。
- 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid, Mono(4-nitrophenyl) ester的英文名称是什么?
- 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid, Mono(4-nitrophenyl) ester的英文名称为 DOTA-mono(4-nitrophenyl) ester。
- 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid, Mono(4-nitrophenyl) ester还有哪些别名?
- 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid, Mono(4-nitrophenyl) ester又称 DOTA单对硝基苯酯、DOTA-单(4-硝基苯基)酯、1,4,7,10-四氮杂环十二烷-1,4,7,10-四乙酸单(4-硝基苯基)酯。
- 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid, Mono(4-nitrophenyl) ester有哪些供应商和生产厂家?
- 掌上化工当前收录 1 条1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid, Mono(4-nitrophenyl) ester供应报价,来自 1 家供应商,可按地区、纯度、级别筛选对比。
- 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid, Mono(4-nitrophenyl) ester的供应商主要分布在哪些地区?
- 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid, Mono(4-nitrophenyl) ester的供应商主要分布在 上海市(1 条) 等地。
- 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid, Mono(4-nitrophenyl) ester有哪些级别可选?
- 平台上1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid, Mono(4-nitrophenyl) ester的供应级别包括 工业级。
- 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid, Mono(4-nitrophenyl) ester的报价单位是什么?
- 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid, Mono(4-nitrophenyl) ester的报价单位主要有 千克。
- 哪里可以查到1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid, Mono(4-nitrophenyl) ester的价格?
- 掌上化工1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid, Mono(4-nitrophenyl) ester产品页汇总了各供应商的最新报价与规格,地址:/chemicals/474424-15-2/。部分供应商价格为电议,可通过页面上的询价功能直接获取。
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