Boc-(R)-3-氨基-4-(2,4,5-三氟苯基)丁酸 (CAS No.486460-00-8)
- 物化性质
- 白色至类白色结晶粉末;易溶于DMSO、DMF、甲醇、乙醇等有机溶剂,微溶于水;具有羧酸和叔丁氧羰基氨基结构,常规条件下稳定;在酸性条件下可脱除Boc保护基。应密封、避光、2–8°C冷藏保存。
- 技术参数
- HPLC纯度不低于98%。 分子量为333.31。 外观为白色至类白色结晶粉末。 应密封、避光,于2–8°C冷藏保存。 包装规格为1g。
English description(英文原文,共 1349 字符)
Product Name:Boc-(R)-3-amino-4-(2,4,5-trifluorophenyl)butanoic acid
English Name:Boc-(R)-3-amino-4-(2,4,5-trifluorophenyl)butanoic acid
CAS No.:486460-00-8
Aliases:(R)-3-((tert-Butoxycarbonyl)amino)-4-(2,4,5-trifluorophenyl)butanoic acid, N-Boc-(R)-3-amino-4-(2,4,5-trifluorophenyl)butyric acid, Boc-(R)-3-amino-4-(2,4,5-trifluorophenyl)butyric acid
Molecular Formula:C15H18F3NO4
Physical Properties:White to off-white crystalline powder; readily soluble in DMSO, DMF, methanol and ethanol, sparingly soluble in water; contains a carboxylic acid and a tert-butoxycarbonylamino group and is stable under normal conditions; the Boc protecting group can be removed under acidic conditions. Store sealed and protected from light at 2–8°C.
Uses:As a chiral β-amino acid derivative, this product is a key intermediate in the synthesis of DPP-4 inhibitor antidiabetic drugs such as sitagliptin. It is useful in asymmetric synthesis methodology, process development of chiral pharmaceuticals, and structure-activity relationship studies. It is also suitable for drug impurity reference and analytical method development. For research use only.
Technical Specifications:
Purity by HPLC is ≥98%.
Molecular weight is 333.31.
Appearance is white to off-white crystalline powder.
Store sealed and protected from light at 2–8°C.
Packaging size is 1 g.
English Name:Boc-(R)-3-amino-4-(2,4,5-trifluorophenyl)butanoic acid
CAS No.:486460-00-8
Aliases:(R)-3-((tert-Butoxycarbonyl)amino)-4-(2,4,5-trifluorophenyl)butanoic acid, N-Boc-(R)-3-amino-4-(2,4,5-trifluorophenyl)butyric acid, Boc-(R)-3-amino-4-(2,4,5-trifluorophenyl)butyric acid
Molecular Formula:C15H18F3NO4
Physical Properties:White to off-white crystalline powder; readily soluble in DMSO, DMF, methanol and ethanol, sparingly soluble in water; contains a carboxylic acid and a tert-butoxycarbonylamino group and is stable under normal conditions; the Boc protecting group can be removed under acidic conditions. Store sealed and protected from light at 2–8°C.
Uses:As a chiral β-amino acid derivative, this product is a key intermediate in the synthesis of DPP-4 inhibitor antidiabetic drugs such as sitagliptin. It is useful in asymmetric synthesis methodology, process development of chiral pharmaceuticals, and structure-activity relationship studies. It is also suitable for drug impurity reference and analytical method development. For research use only.
Technical Specifications:
Purity by HPLC is ≥98%.
Molecular weight is 333.31.
Appearance is white to off-white crystalline powder.
Store sealed and protected from light at 2–8°C.
Packaging size is 1 g.
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常见问题
- Boc-(R)-3-氨基-4-(2,4,5-三氟苯基)丁酸的 CAS 号是多少?
- Boc-(R)-3-氨基-4-(2,4,5-三氟苯基)丁酸的 CAS 号是 486460-00-8。
- Boc-(R)-3-氨基-4-(2,4,5-三氟苯基)丁酸的分子式和分子量是什么?
- Boc-(R)-3-氨基-4-(2,4,5-三氟苯基)丁酸的分子式为 C15H18F3NO4。
- Boc-(R)-3-氨基-4-(2,4,5-三氟苯基)丁酸的英文名称是什么?
- Boc-(R)-3-氨基-4-(2,4,5-三氟苯基)丁酸的英文名称为 Boc-(R)-3-amino-4-(2,4,5-trifluorophenyl)butanoic acid。
- Boc-(R)-3-氨基-4-(2,4,5-三氟苯基)丁酸还有哪些别名?
- Boc-(R)-3-氨基-4-(2,4,5-三氟苯基)丁酸又称 (R)-3-(叔丁氧羰基氨基)-4-(2,4,5-三氟苯基)丁酸、N-Boc-(R)-3-氨基-4-(2,4,5-三氟苯基)丁酸、叔丁氧羰基-(R)-3-氨基-4-(2,4,5-三氟苯基)丁酸。
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