来那替尼 (CAS No.698387-09-6)
- 物化性质
- 白色至类白色结晶粉末，无臭。易溶于二甲基亚砜（DMSO）和N,N-二甲基甲酰胺（DMF），微溶于甲醇、乙醇，几乎不溶于水。密度（预测值）约1.30 g/cm³，熔点约186-188°C（分解）。
- 纯度
- ≥99%（HPLC）
- 外观
- 白色至类白色结晶粉末
- 溶解性
- 溶于DMSO、DMF，微溶于甲醇，几乎不溶于水
- 储存条件
- 密封避光，2-8°C保存
English description（英文原文，共 1149 字符）
Product Name:Neratinib
English Name:Neratinib
CAS No.:698387-09-6
Aliases:Neratinib, HKI-272
Molecular Formula:C30H29ClN6O3
Physical Properties:White to off-white crystalline powder, odorless. Freely soluble in dimethyl sulfoxide (DMSO) and N,N-dimethylformamide (DMF), slightly soluble in methanol and ethanol, practically insoluble in water. Predicted density approximately 1.30 g/cm³, melting point approximately 186-188°C (decomposes).
Uses:Neratinib is an irreversible HER2 (ErbB2) and EGFR (ErbB1) receptor tyrosine kinase inhibitor that forms covalent bonds with the receptors to persistently block downstream signaling pathways. It is primarily used as adjuvant therapy after surgery for patients with HER2-positive early-stage breast cancer, significantly reducing the risk of disease recurrence. It is also used in research on other HER2-driven tumors.
Technical Specifications:
Purity: ≥99% (HPLC)
Molecular weight: 557.04
Appearance: White to off-white crystalline powder
Solubility: Soluble in DMSO and DMF, slightly soluble in methanol, practically insoluble in water
Storage: Store sealed and protected from light at 2-8°C
English Name:Neratinib
CAS No.:698387-09-6
Aliases:Neratinib, HKI-272
Molecular Formula:C30H29ClN6O3
Physical Properties:White to off-white crystalline powder, odorless. Freely soluble in dimethyl sulfoxide (DMSO) and N,N-dimethylformamide (DMF), slightly soluble in methanol and ethanol, practically insoluble in water. Predicted density approximately 1.30 g/cm³, melting point approximately 186-188°C (decomposes).
Uses:Neratinib is an irreversible HER2 (ErbB2) and EGFR (ErbB1) receptor tyrosine kinase inhibitor that forms covalent bonds with the receptors to persistently block downstream signaling pathways. It is primarily used as adjuvant therapy after surgery for patients with HER2-positive early-stage breast cancer, significantly reducing the risk of disease recurrence. It is also used in research on other HER2-driven tumors.
Technical Specifications:
Purity: ≥99% (HPLC)
Molecular weight: 557.04
Appearance: White to off-white crystalline powder
Solubility: Soluble in DMSO and DMF, slightly soluble in methanol, practically insoluble in water
Storage: Store sealed and protected from light at 2-8°C
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常见问题
- 来那替尼的 CAS 号是多少？
- 来那替尼的 CAS 号是 698387-09-6。
- 来那替尼的分子式和分子量是什么？
- 来那替尼的分子式为 C30H29ClN6O3，分子量约 557.04。
- 来那替尼的英文名称是什么？
- 来那替尼的英文名称为 Neratinib。
- 来那替尼还有哪些别名？
- 来那替尼又称 奈拉替尼、HKI-272。
- 来那替尼有哪些供应商和生产厂家？
- 掌上化工当前收录 1 条来那替尼供应报价，来自 1 家供应商，可按地区、纯度、级别筛选对比。
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- 掌上化工来那替尼产品页汇总了各供应商的最新报价与规格，地址：/chemicals/698387-09-6/。部分供应商价格为电议，可通过页面上的询价功能直接获取。
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