反式-4-(马来酰亚胺甲基)环己烷羧酸（69907-67-1） (CAS No.69907-67-1)
- 中文别名
- 反式-4-(马来酰亚胺基甲基)环己烷-1-羧酸；MCC；4-马来酰亚胺甲基环己烷羧酸
- 英文名称
- Trans-4-(Maleimidomethyl)cyclohexanecarboxylic Acid
- 分子式
- C12H15NO4
- 所属类别
- 试剂实验设备
- 物化性质
- 白色至类白色结晶性固体，溶于二甲基亚砜（DMSO）、N,N-二甲基甲酰胺（DMF）等有机溶剂，微溶于水。具有马来酰亚胺基团，可与巯基发生特异性反应。
- 外观
- 白色至类白色结晶性粉末
- 纯度
- ≥98%（HPLC）
- 熔点
- 140-143℃
- 溶解性
- 溶于DMSO、DMF，微溶于甲醇和水
English description（英文原文，共 1136 字符）
Product Name:Trans-4-(Maleimidomethyl)cyclohexanecarboxylic Acid
English Name:Trans-4-(Maleimidomethyl)cyclohexanecarboxylic Acid
CAS No.:69907-67-1
Aliases:trans-4-(Maleimidomethyl)cyclohexane-1-carboxylic acid, MCC, 4-Maleimidomethylcyclohexanecarboxylic acid
Molecular Formula:C12H15NO4
Physical Properties:White to off-white crystalline solid. Soluble in organic solvents such as dimethyl sulfoxide (DMSO) and N,N-dimethylformamide (DMF), slightly soluble in water. The maleimide group reacts specifically with sulfhydryl groups.
Uses:This compound is a key intermediate in the synthesis of the heterobifunctional crosslinker SMCC and is widely used in the preparation of antibody-drug conjugates (ADCs). Its maleimide group selectively couples with thiol groups on proteins or antibodies, enabling site-specific modification of biomolecules. It is also used to prepare crosslinking reagents with a rigid cyclohexane spacer.
Technical Specifications:
Appearance: white to off-white crystalline powder
Purity: ≥98% (HPLC)
Melting point: 140-143°C
Solubility: soluble in DMSO and DMF, slightly soluble in methanol and water
English Name:Trans-4-(Maleimidomethyl)cyclohexanecarboxylic Acid
CAS No.:69907-67-1
Aliases:trans-4-(Maleimidomethyl)cyclohexane-1-carboxylic acid, MCC, 4-Maleimidomethylcyclohexanecarboxylic acid
Molecular Formula:C12H15NO4
Physical Properties:White to off-white crystalline solid. Soluble in organic solvents such as dimethyl sulfoxide (DMSO) and N,N-dimethylformamide (DMF), slightly soluble in water. The maleimide group reacts specifically with sulfhydryl groups.
Uses:This compound is a key intermediate in the synthesis of the heterobifunctional crosslinker SMCC and is widely used in the preparation of antibody-drug conjugates (ADCs). Its maleimide group selectively couples with thiol groups on proteins or antibodies, enabling site-specific modification of biomolecules. It is also used to prepare crosslinking reagents with a rigid cyclohexane spacer.
Technical Specifications:
Appearance: white to off-white crystalline powder
Purity: ≥98% (HPLC)
Melting point: 140-143°C
Solubility: soluble in DMSO and DMF, slightly soluble in methanol and water
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常见问题
- 反式-4-(马来酰亚胺甲基)环己烷羧酸（69907-67-1）的 CAS 号是多少？
- 反式-4-(马来酰亚胺甲基)环己烷羧酸（69907-67-1）的 CAS 号是 69907-67-1。
- 反式-4-(马来酰亚胺甲基)环己烷羧酸（69907-67-1）的分子式和分子量是什么？
- 反式-4-(马来酰亚胺甲基)环己烷羧酸（69907-67-1）的分子式为 C12H15NO4。
- 反式-4-(马来酰亚胺甲基)环己烷羧酸（69907-67-1）的英文名称是什么？
- 反式-4-(马来酰亚胺甲基)环己烷羧酸（69907-67-1）的英文名称为 Trans-4-(Maleimidomethyl)cyclohexanecarboxylic Acid。
- 反式-4-(马来酰亚胺甲基)环己烷羧酸（69907-67-1）还有哪些别名？
- 反式-4-(马来酰亚胺甲基)环己烷羧酸（69907-67-1）又称 反式-4-(马来酰亚胺基甲基)环己烷-1-羧酸、MCC、4-马来酰亚胺甲基环己烷羧酸。
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